Fig. 3

Metabolic fasting parameters. Results of serum total bilirubin, insulin requirements to maintain normoglycemia, serum urea, serum IGF-I, and plasma BOH are shown on the study day for both randomization groups. For bilirubin, urea, IGF-I, and BOH measurements, blood samples were obtained at the start of the protocol, at the end of the first study interval, and at the end of the second study interval. For insulin requirements, insulin administration was averaged per hour for the 24 h before the study day to obtain a baseline value and averaged per hour for both study intervals. Reported p values were obtained with repeated measures ANOVA. Lines represent means, and bars represent standard errors of the means. IGF-I, insulin-like growth factor I; BOH, beta-hydroxybutyrate