Table 6 Multivariable analysis
ICU mortality | Hospital mortality | |||||
|---|---|---|---|---|---|---|
OR | 95% CI | p value | OR | 95% CI | p value | |
Age | 1.02 | 1.01–1.03 | < 0.001 | 1.02 | 1.01–1.03 | 0.001 |
Male sex | 1.21 | 0.84–1.73 | 0.30 | 1.23 | 0.89–1.70 | 0.23 |
BMI | ||||||
< 20 | 2.43 | 1.01–5.82 | 3.09 | 1.32–7.23 | ||
20 to < 25 | 1 | 0.22 | 1 | 0.037 | ||
25 to < 30 | 0.90 | 0.59–1.39 | 0.95 | 0.64–1.43 | ||
30 to < 40 | 0.84 | 0.53–1.31 | 0.86 | 0.57–1.31 | ||
40 or higher | 0.86 | 0.42–1.78 | 1.53 | 0.79–2.97 | ||
SOFA score on the 1st day of CRRT | 1.17 | 1.11–1.23 | < 0.001 | 1.13 | 1.08–1.16 | < 0.001 |
Highest arterial lactate concentration on 1st day of CRRT (μmol/l) | 1.03 | 0.98–1.07 | 0.23 | 1.04 | 1.00–1.08 | 0.065 |
Hb on 1st day of CRRT (per 10 g/dl) | 0.99 | 0.90–1.09 | 0.86 | 0.98 | 0.89–1.07 | 0.61 |
Daily noradrenaline dose [μg], mean* | ||||||
0 | 1 | < 0.001 | 1 | 0.002 | ||
1–4999 | 0.87 | 0.50–1.51 | 0.92 | 0.56–1.51 | ||
5000–9999 | 0.96 | 0.48–1.93 | 1.12 | 0.62–2.03 | ||
10,000–49,999 | 2.60 | 1.62–4.17 | 1.94 | 1.25–3.00 | ||
≥ 50,000 | 2.77 | 1.40–5.50 | 2.10 | 1.06–4.19 | ||
Cumulative FB at CRRT initiation (per 1000 ml) | 1.01 | 0.97–1.05 | 0.80 | 1.01 | 0.97–1.05 | 0.59 |
Delta cumulative FB | ||||||
No nadir reached | 1 | 0.048 | 1 | 0.010 | ||
< 2500 ml reduction | 0.84 | 0.48–1.46 | 0.77 | 0.54–1.29 | ||
2500–4999 ml reduction | 0.57 | 0.36–0.91 | 0.67 | 0.43–1.03 | ||
≥ 5000 ml reduction | 0.57 | 0.33–0.99 | 0.43 | 0.26–0.71 | ||