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Table 2 Variation of [TIMP-2]*[IGFBP7] at different time points

From: Urine cell cycle arrest biomarkers distinguish poorly between transient and persistent AKI in early septic shock: a prospective, multicenter study

Parameters Sample (n) Total cohort Transient AKI Persistent AKI p value
[TIMP-2]*[IGFBP7] at 0 h ([ng/ml]2/1000) 184 1.26 [0.26–4.00] 0.75 [0.20–2.12] 2.21 [0.81–4.90] < 0.001
[TIMP-2]*[IGFBP7] at 6 h ([ng/ml]2/1000) 172 0.71 [0.22–2.86] 0.37 [0.13–1.38] 2.02 [0.54–5.43] < 0.001
[TIMP-2]*[IGFBP7] at 12 h ([ng/ml]2/1000) 165 0.50 [0.19–1.59] 0.33 [0.13–0.78] 1.19 [0.30–3.8] < 0.001
[TIMP-2]*[IGFBP7] at 24 h ([ng/ml]2/1000) 156 0.46 [0.16–1.18] 0.32 [0.12–0.86] 0.69 [0.26–2.36] < 0.001
∆[TIMP-2]*[IGFBP7] 0 to 6 h (%) 172 − 20.0 [− 76.4–74.7] 11.3 [− 48.6–111.1] − 36.5 [− 79.4–49.7] 0.04
∆[TIMP-2]*[IGFBP7] 0 to 12 h (%) 165 − 39.1 [− 77.2–56.4] − 19.0 [− 70.6–100.4] − 50.0 [− 84.0–50.0] 0.13
∆[TIMP-2]*[IGFBP7] 12 to 24 h (%) 156 0.0 [− 77.3–56.4] 3.7 [− 76.0–48.7] 0.0 [− 66.7–51.5] 0.99
  1. Median and interquartile range