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Table 2 Variation of [TIMP-2]*[IGFBP7] at different time points

From: Urine cell cycle arrest biomarkers distinguish poorly between transient and persistent AKI in early septic shock: a prospective, multicenter study

Parameters

Sample (n)

Total cohort

Transient AKI

Persistent AKI

p value

[TIMP-2]*[IGFBP7] at 0 h ([ng/ml]2/1000)

184

1.26 [0.26–4.00]

0.75 [0.20–2.12]

2.21 [0.81–4.90]

< 0.001

[TIMP-2]*[IGFBP7] at 6 h ([ng/ml]2/1000)

172

0.71 [0.22–2.86]

0.37 [0.13–1.38]

2.02 [0.54–5.43]

< 0.001

[TIMP-2]*[IGFBP7] at 12 h ([ng/ml]2/1000)

165

0.50 [0.19–1.59]

0.33 [0.13–0.78]

1.19 [0.30–3.8]

< 0.001

[TIMP-2]*[IGFBP7] at 24 h ([ng/ml]2/1000)

156

0.46 [0.16–1.18]

0.32 [0.12–0.86]

0.69 [0.26–2.36]

< 0.001

∆[TIMP-2]*[IGFBP7] 0 to 6 h (%)

172

− 20.0 [− 76.4–74.7]

11.3 [− 48.6–111.1]

− 36.5 [− 79.4–49.7]

0.04

∆[TIMP-2]*[IGFBP7] 0 to 12 h (%)

165

− 39.1 [− 77.2–56.4]

− 19.0 [− 70.6–100.4]

− 50.0 [− 84.0–50.0]

0.13

∆[TIMP-2]*[IGFBP7] 12 to 24 h (%)

156

0.0 [− 77.3–56.4]

3.7 [− 76.0–48.7]

0.0 [− 66.7–51.5]

0.99

  1. Median and interquartile range