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Fig. 4 | Critical Care

Fig. 4

From: Microbiota-driven interleukin-17 production provides immune protection against invasive candidiasis

Fig. 4

Protection provided by administration of rIL-17A for ABX mice during invasive candidiasis. a Plot of weight loss over time after infection in comparison to starting weight for rIL-17A treatment group and control group (n = 5). b Survival analysis of both groups after infection (n = 8). c–f Serum concentrations of IFN-γ (c) (n = 6), fungal burden of the kidneys (d) (n = 7), representative image of H&E-stained kidney (e) and corresponding pathological scores (f) (n = 5) in mice from both rIL-17A treatment group and control group at day 3 after infection. Data were expressed as mean ± SEM. P values were analyzed by two-way ANOVA (a), log-rank test (b), and Mann-Whitney U test (c, d, f). Two-tailed P values < 0.05 were considered statistically significant. Results are representative of three independent experiments

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