Fig. 1

Decreased survival ability of ABX mice in invasive candidiasis. a Fecal bacteria quantification of non-infected ABX and CNV mice in aerobic and anaerobic environments (n = 4). b Feces smear stained using Gram stain from non-infected ABX and CNV mice. c Representative examples of H&E-stained kidney from non-infected ABX and CNV mice. d The serum concentrations of ALT, AST, BUN, and creatinine of non-infected ABX and CNV mice. e Weight curve of non-infected ABX and CNV mice. f Body weight loss of ABX and CNV mice were daily monitored after intravenous injection with fungal yeasts (2 × 105 CFUs C. albicans strain SC5314) and depicted with plot (n = 6). g Survival analysis of the ABX and CNV mice after injection (n = 10). Data were expressed as mean ± SEM, and P values were analyzed by Mann-Whitney U test (a, d), two-way ANOVA (c), and log-rank test (d). Two-tailed P values < 0.05 were considered statistically significant. Results are representative of three independent experiments