From: Significance of body temperature in elderly patients with sepsis
 | Non-elderly (< 75 years) (n = 628) | Elderly (≥ 75 years) (n = 520) | P value |
---|---|---|---|
Characteristics | |||
 Age, years | 65 (55–70) | 82 (78–86) | < 0.0001 |
 Male sex, n (%) | 405 (64.5) | 288 (55.4) | 0.0017 |
 Suspected site of infection, n (%) | |||
  Lung | 193 (30.7) | 164 (31.5) | 0.77 |
  Intra-abdominal | 150 (23.9) | 145 (27.9) | 0.12 |
  Urinary tract | 102 (16.2) | 116 (22.3) | 0.0091 |
  Soft tissue | 79 (12.6) | 35 (6.7) | 0.0010 |
  Othersa | 104 (16.6) | 60 (11.5) | 0.015 |
 Septic shock, n (%) | 387 (61.6) | 331 (63.7) | 0.48 |
 Body mass index | 22.5 (19.3–25.2) | 20.8 (18.6–23.9) | < 0.0001 |
 Chronic steroid use, n (%) | 86 (13.7) | 55 (10.6) | 0.11 |
 Comorbidity, n (%) | |||
  Diabetes mellitus | 155 (24.7) | 107 (20.6) | 0.099 |
  Stroke | 55 (8.8) | 78 (15.0) | 0.0010 |
  Malignancy | 101 (16.1) | 77 (14.8) | 0.55 |
  Heart failure | 49 (7.8) | 74 (14.2) | 0.0005 |
  Chronic kidney disease | 39 (6.2) | 41 (7.9) | 0.27 |
  Liver disease | 43 (6.8) | 25 (4.8) | 0.15 |
  Chronic lung disease | 39 (6.2) | 41 (7.9) | 0.27 |
 Charlson comorbidity index | 1 (0–2) | 1 (0–2) | 0.014 |
 SOFA score | 9 (6–11) | 9 (6–11) | 0.73 |
 APACHE II score | 22 (16–29) | 23 (18–30) | 0.085 |
 Vital signs on day 1b | |||
  Body temperature, °C | 38.0 (36.8–39.0) | 37.6 (36.7–38.5) | 0.0003 |
  Heart rate, beats/min | 114 (96–133) | 108 (91–123) | < 0.0001 |
  Mean arterial pressure, mmHg | 63 (53–78) | 63 (52–78) | 0.65 |
  Systolic blood pressure, mmHg | 86 (72–110) | 90 (72–110) | 0.38 |
  Respiratory rate, breath/min | 25 (20–32) | 25 (20–32) | 0.63 |
Outcome | |||
 28-day in-hospital mortality, n (%) | 90 (14.3) | 100 (19.2) | 0.026 |
 90-day in-hospital mortality, n (%) | 123 (19.6) | 130 (25.0) | 0.028 |