Bedside ultrasound measurement of optic nerve sheath diameter in patients with sepsis: a prospective observational study

Table 1 Patient’s characteristics

Characteristic	All sepsis patients^#	SAE*	Non-SAE*	SAE recovery*
Gender (male, n%)	54 (60.0%)	30 (58.8%)	41 (57.7%)	12 (60%)
Age (years, median [IQR])	45 [32, 69]	49 [32, 70]	45 [32, 67]	58 [38, 76]
APACHE II score (median [IQR])	14 [9, 17]	22 [19.5, 28.5]	12 [9, 15]	12.5 [10, 15]
APACHE II score without GCS	14 [9.25, 18.75]	19 [15, 23]	12 [9, 15]	12.5 [10, 15]
SOFA score (median [IQR])	8 [5, 12]	13 [12, 17]	6 [5, 9]	5 [3, 6]
GCS score (median [IQR])	15 [15, 15]	12 [6, 14]	15	15
Serum lactic acid (median [IQR])	2.7 [1.9, 5.1]	6.7 [2.45, 15]	2.1 [1.45, 2.75]	2.4 [2.1, 4.375]
PCT (median [IQR])	3.5 [2.1, 8]	17 [7.5, 36]	2.4 [1.8, 4.5]	2.4 [1.45, 3.3]
Albumin (median [IQR])	30.1 [27.1, 32.1]	28.9 [25.5, 31.05]	30.5 [27.6, 32.2]	34.75 [29.7, 36]
MV time (hours, median [IQR])	33.5 [0, 67]	63 [50, 98.5]	5 [0, 52]	63 [33, 91.5]
In-hospital days (median [IQR])	16 [10, 20]	15 [9.5, 22]	17 [11, 22]	16 [14.25, 24.25]
In-ICU days (median [IQR])	12.5 [9, 18]	12 [9, 20]	15 [9, 20]	14.5 [10.75, 18.5]
28-day mortality (n%)	45 (50%)	31 (60.7%)	33 (46.4%)	0
ONSD (mm)	5.4 [5, 5.7]	5.9 [5.6, 6.25]	5.1 [4.75, 5.4]	5.35 [5.075, 5.5]

Data are median [IQR] or n (%)
Non-SAE sepsis patients with a clear head, without SAE; SAE recovery SAE patients who received effective therapy and whose GCS score recovered to 15 points; APACHE II Acute Physiology and Chronic Health Evaluation II; SOFA Sequential Organ Failure Assessment; GCS Glasgow Coma Scale; PCT procalcitonin; IQR interquartile range; MV mechanical ventilation; ICU intensive care unit; ONSD optic nerve sheath diameter
^#Patient data collected in the first 24 h after admission
*Patient data collected in the first 24 h after the diagnosis of SAE or SAE recovery

ISSN: 1364-8535