Table 1 Data collection of variables for HLH-2004 criteria and HScore
Variables | Time range with regard to maximum ferritin (when not assessed at day of ferritin maximum) |
|---|---|
Hemoglobin, platelets, white blood cell count [min] | ± 3 days |
Fibrinogen [min] | ± 3 days |
Triglycerides [max] | ± 5 days |
Body temperature [max] | ± 5 days |
AST [max] | ± 3 days |
NK cell activity, CD107a [max] | ± 10 days |
sIL-2R | Study period |
Hepatomegaly, splenomegaly | Study period |
Hemophagocytosis | Study period |
Preexisting immunosuppression | Obtained from medical records before study period |