Table 3 Univariate analysis of ICU survival associated factors
From: Severe diffuse alveolar hemorrhage related to autoimmune disease: a multicenter study
Parameter | Univariate analysis | |
|---|---|---|
SHR 95%CI | p value | |
Age (per 10 years) | 0.87 (0.79–0.95) | 0.0016 |
Sex | 1.12 (0.75–1.7) | 0.58 |
Charlson comorbidity index | 0.88 (0.81–0.97) | 0.0078 |
Chronic respiratory failure | 0.73 (0.29–1.82) | 0.49 |
Chronic cardiac failure | 0.34 (0.16–0.74) | 0.0063 |
Chronic renal failure | 0.59 (0.3–1.17) | 0.13 |
Steroid treatment | 0.78 (0.44–1.37) | 0.38 |
Connective tissue disorder | 1.35 (0.82–2.22) | 0.24 |
Systemic lupus | 1.07 (0.48–2.41) | 0.86 |
Antiphospholipid syndrome | 2.26 (1.35–3.78) | 0.0018 |
Other systemic disease | 0.87 (0.36–2.09) | 0.76 |
Vasculitis | 1.35 (0.82–2.22) | 0.24 |
ANCA-associated vasculitis | 0.95 (0.62–1.45) | 0.8 |
Goodpasture syndrome | 1.08 (0.7–1.66) | 0.73 |
Cryoglobulin-associated vasculitis | 0.17 (0.02–1.68) | 0.13 |
IgA-associated vasculitis | 0.49 (0.15–1.6) | 0.24 |
Relapse | 1.07 (0.63–1.81) | 0.81 |
Hemoptysis | 1.18 (0.79–1.77) | 0.42 |
Acute respiratory failure | 0.57 (0.37–0.89) | 0.014 |
Renal involvement | 0.73 (0.46–1.14) | 0.17 |
Digestive involvement | 1.31 (0.45–3.85) | 0.62 |
Nervous system involvement | 1.21 (0.78–1.87) | 0.39 |
Joint involvement | 0.8 (0.48–1.34) | 0.41 |
Skin involvement | 0.81 (0.48–1.36) | 0.43 |
Other systemic disease manifestations | 1.1 (0.93–1.3) | 0.25 |
SAPS II | 0.97 (0.96–0.99) | < 0.0001 |
Oxygen flow | 0.95 (0.91–0.98) | 0.0032 |
PAO2 over FiO2 ratio (per 10 points) | 1.02 (1–1.04) | 0.0099 |
Time (days) from dyspnea onset to ICU admission | (0.98–1) | 0.13 |
Time (days) from hospital admission to ICU admission | 1.01 (0.98–1.04) | 0.6 |
Hemoglobin at ICU admission | 0.97 (0.89–1.05) | 0.41 |
Lymphocytes at ICU admission | 2.51 (1.6–3.95) | < 0.0001 |
Neutrophil count at ICU admission | 1.02 (0.98–1.06) | 0.45 |
Platelets count at ICU admission (per 10G/L) | 1.01 (0.99–1.02) | 0.36 |
Creatinine at ICU admission (per 10 μmol/L) | 1 (0.99–1.01) | 0.72 |
Urine protein/creatinine ratio | 0.97 (0.46–2.02) | 0.93 |
LDH at ICU admission (per 100UI/L) | 0.98 (0.94–1.02) | 0.31 |
Vasopressor use | 0.29 (0.18–0.47) | < 0.0001 |