Table 2 Univariate analysis of factors associated with mechanical ventilation requirement
From: Severe diffuse alveolar hemorrhage related to autoimmune disease: a multicenter study
Parameters | No invasive ventilation n = 52 | Invasive ventilation n = 52 | p value |
|---|---|---|---|
Age, years, median [IQR] | 50 [29–62] | 58 [39–70] | 0.12 |
Charlson comorbidity index, median [IQR] | 3 [1.3–4.8] | 3 [1–4] | 0.59 |
Vasculitis, yes, n (%) | 38 (73%) | 41 (79%) | 0.65 |
Hemoptysis, yes, n (%) | 30 (58%) | 23 (44%) | 0.24 |
Acute respiratory failure, n (%) | 28 (54%) | 50 (96%) | < 0.0001 |
Renal involvement, yes, n (%) | 40 (77%) | 43 (84%) | 0.46 |
SAPS II, median [IQR] | 29 [19–37] | 44 [33–56] | < 0.0001 |
PaO2/FiO2 ratio, median [IQR] | 205 [123–263] | 108 [75–190] | 0.0003 |
Time (days) from dyspnea to ICU admission, days, median [IQR] | 6 [1–23] | 5 [1–16] | 0.70 |
Hemoglobin at day 1, median [IQR] | 8.3 [7.4–9.5] | 8.6 [7.2–9.5] | 0.85 |
Neutrophil count at day 1, median [IQR] | 8.2 [6.4–10.2] | 10.6 [7.6–18.0] | 0.05 |
LDH at day 1, UI/L, median[IQR] | 432 [317–626] | 679 [409–1213] | 0.010 |