Table 4 ICU-related outcomes and mortality. ICU intensive care unit, KDIGO Kidney Disease Improving Global Outcomes
From: Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study
Overall, n = 316 | Abdominal, n = 140 (44%) | Pulmonary, n = 59 (19%) | S/ST, n = 56 (18%) | GU, n = 40 (12%) | Vascular, n = 21 (7%) | p value | |
|---|---|---|---|---|---|---|---|
ICU days, median (25th, 75th) | 7 (3, 17) | 9 (3,18) | 15 (8,21) | 5 (3, 10) | 3 (2,4) | 9 (5,18) | < 0.01 |
Need for mechanical ventilation, n (%) | 209 (66) | 100 (71) | 51 (86) | 34 (61) | 11 (28) | 13 (62) | < 0.01 |
Ventilator-free days, median (25th, 75th) | 27 (22,30) | 27 (21,30) | 25 (18,28) | 28 (26,30) | 30 (28,30) | 28 (23,30) | < 0.01 |
Acute kidney injury, n (%) | 188 (60) | 79 (56) | 31 (52) | 39 (70) | 25 (63) | 14 (68) | 0.32 |
KDIGO stage 1 | 80 (43) | 23 (29) | 19 (62) | 18 (32) | 15 (38) | 5 (24) | 0.01 |
KDIGO stage 2 | 65 (34) | 33 (42) | 6 (19) | 16 (29) | 7 (18) | 3 (14) | 0.10 |
KDIGO stage 3 | 43 (23) | 23 (29) | 6 (19) | 5 (9) | 3 (8) | 6 (29) | 0.12 |
Multiple organ failure, n (%) | 48 (15) | 24 (17) | 11 (19) | 5 (9) | 4 (10) | 4 (19) | 0.43 |
Secondary infections/patient, mean (SD) | 0.5 (0.9) | 0.8 (1) | 0.5 (0.8) | 0.3 (0.6) | 0.1 (0.4) | 0.4 (0.7) | < 0.01 |
Secondary infections/100 hospital days | 2.3 (4.8) | 3.4 (6.2) | 2.2 (4.0) | 1.0 (2.2) | 0.3 (1.0) | 1.4 (2.3) | < 0.01 |
Clinical trajectory | |||||||
Early death (< 14 days), n (%) | 14 (4) | 9 (6) | 1 (2) | 1 (2) | 1 (2) | 2 (10) | 0.32 |
Rapid recovery, n (%) | 194 (62) | 80 (57) | 26 (44) | 42 (75) | 35 (88) | 11 (52) | < 0.01 |
Chronic critical illness, n (%) | 108 (34) | 51 (37) | 32 (54) | 13 (23) | 4 (10) | 8 (38) | < 0.01 |
Discharge disposition, n (%) | |||||||
“Good” disposition | 176 (56) | 72 (51) | 31 (53) | 34 (61) | 32 (80) | 7 (33) | < 0.01 |
Home | 60 (34) | 23 (32) | 6 (19) | 8 (23) | 22 (69) | 1 (14) | |
Homecare | 97 (55) | 43 (60) | 17 (55) | 23 (68) | 9 (28) | 5 (72) | |
Rehab | 19 (11) | 6 (8) | 8 (26) | 3 (9) | 1 (3) | 1 (14) | |
“Poor” disposition | 140 (44) | 68 (49) | 28 (47) | 22 (39) | 8 (20) | 14 (67) | < 0.01 |
Long-term care hospital | 48 (34) | 26 (38) | 10 (36) | 8 (36) | 3 (38) | 1 (7) | |
Skilled nursing | 48 (34) | 21 (31) | 8 (28) | 9 (41) | 3 (38) | 7 (50) | |
Another hospital | 10 (7) | 2 (3) | 3 (11) | 4 (18) | 1 (12) | 0 (0) | |
Hospice | 7 (5) | 5 (7) | 0 (0) | 0 (0) | 0 (0) | 2 (14) | |
Death | 27 (20) | 14 (21) | 7 (25) | 1 (5) | 1 (12) | 4 (29) | |
30-day mortality, n (%) | 31 (10) | 19 (14) | 5 (8) | 1 (2) | 2 (5) | 4 (19) | 0.03 |
180-day mortality, n (%) | 59 (19) | 31 (22) | 11 (19) | 4 (7) | 5 (12) | 8 (38) | 0.01 |
1-year mortality, n (%) | 67 (21) | 36 (26) | 12 (20) | 5 (9) | 5 (12) | 9 (43) | < 0.01 |