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Table 4 ICU-related outcomes and mortality. ICU intensive care unit, KDIGO Kidney Disease Improving Global Outcomes

From: Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study

 Overall, n = 316Abdominal, n = 140 (44%)Pulmonary, n = 59 (19%)S/ST, n = 56 (18%)GU, n = 40 (12%)Vascular, n = 21 (7%)p value
ICU days, median (25th, 75th)7 (3, 17)9 (3,18)15 (8,21)5 (3, 10)3 (2,4)9 (5,18)< 0.01
Need for mechanical ventilation, n (%)209 (66)100 (71)51 (86)34 (61)11 (28)13 (62)< 0.01
Ventilator-free days, median (25th, 75th)27 (22,30)27 (21,30)25 (18,28)28 (26,30)30 (28,30)28 (23,30)< 0.01
Acute kidney injury, n (%)188 (60)79 (56)31 (52)39 (70)25 (63)14 (68)0.32
KDIGO stage 180 (43)23 (29)19 (62)18 (32)15 (38)5 (24)0.01
KDIGO stage 265 (34)33 (42)6 (19)16 (29)7 (18)3 (14)0.10
KDIGO stage 343 (23)23 (29)6 (19)5 (9)3 (8)6 (29)0.12
Multiple organ failure, n (%)48 (15)24 (17)11 (19)5 (9)4 (10)4 (19)0.43
Secondary infections/patient, mean (SD)0.5 (0.9)0.8 (1)0.5 (0.8)0.3 (0.6)0.1 (0.4)0.4 (0.7)< 0.01
Secondary infections/100 hospital days2.3 (4.8)3.4 (6.2)2.2 (4.0)1.0 (2.2)0.3 (1.0)1.4 (2.3)< 0.01
Clinical trajectory
 Early death (< 14 days), n (%)14 (4)9 (6)1 (2)1 (2)1 (2)2 (10)0.32
 Rapid recovery, n (%)194 (62)80 (57)26 (44)42 (75)35 (88)11 (52)< 0.01
 Chronic critical illness, n (%)108 (34)51 (37)32 (54)13 (23)4 (10)8 (38)< 0.01
Discharge disposition, n (%)
 “Good” disposition176 (56)72 (51)31 (53)34 (61)32 (80)7 (33)< 0.01
 Home60 (34)23 (32)6 (19)8 (23)22 (69)1 (14) 
 Homecare97 (55)43 (60)17 (55)23 (68)9 (28)5 (72) 
 Rehab19 (11)6 (8)8 (26)3 (9)1 (3)1 (14) 
 “Poor” disposition140 (44)68 (49)28 (47)22 (39)8 (20)14 (67)< 0.01
 Long-term care hospital48 (34)26 (38)10 (36)8 (36)3 (38)1 (7) 
 Skilled nursing48 (34)21 (31)8 (28)9 (41)3 (38)7 (50) 
 Another hospital10 (7)2 (3)3 (11)4 (18)1 (12)0 (0) 
 Hospice7 (5)5 (7)0 (0)0 (0)0 (0)2 (14) 
 Death27 (20)14 (21)7 (25)1 (5)1 (12)4 (29) 
30-day mortality, n (%)31 (10)19 (14)5 (8)1 (2)2 (5)4 (19)0.03
180-day mortality, n (%)59 (19)31 (22)11 (19)4 (7)5 (12)8 (38)0.01
1-year mortality, n (%)67 (21)36 (26)12 (20)5 (9)5 (12)9 (43)< 0.01