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Table 2 Diagnostic test performance of furosemide stress test for AKI progression, renal replacement therapy, and mortality

From: Furosemide stress test as a predictive marker of acute kidney injury progression or renal replacement therapy: a systemic review and meta-analysis

Study

Sensitivity

Specificity

Sample size

Event (AKI progression)

TP

FP

FN

TN

Follow-up period

 Chawla, 2013 [8]

87.1

84.1

77

25

22

8

3

44

14 days

 Elsaegh, 2018 [14]

89.3

93.4

60

28

25

2

3

30

NA

 Martínez, 2016 [16]

66.7

100

20

6

4

0

2

14

30 days

 Matsuura, 2018 [17]

76.5

94.1

51

17

13

2

4

32

7 days

 Pérez-Cruz, 2017 [18]

57.1

95.2

35

14

8

1

6

20

NA

 Saber, 2018 [20]

86.7

68

40

15

13

8

2

17

NA

 Rewa, 2019 [19]

73.9

90

92

23

17

7

6

62

30 days

 Vairakkani, 2019 [22]

82

80.8

80

28

23

10

5

42

14 days

 Venugopal, 2019 [24]

85.7

87.5

62

14

12

6

2

42

NA

Study

Sensitivity

Specificity

Sample size

Event (RRT)

TP

FP

FN

TN

Follow-up period

 Lumlertgul, 2018 [15]

94.4

70.4

162

108

102

16

6

38

28 days

 Martínez, 2016 [16]

75

93.7

20

4

3

1

1

15

30 days

 Matsuura, 2018 [17]

75

79

51

8

6

9

2

34

7 days

 Pérez-Cruz, 2017 [18]

62.5

85.2

35

8

5

4

3

23

NA

 Sakhuja, 2019 [21]

80.9

50.5

687

162

131

260

31

265

1 day

 Venugopal, 2019 [23]

83.3

84

62

12

10

8

2

42

NA

Study

Sensitivity

Specificity

Sample size

Event (mortality)

TP

FP

FN

TN

Follow-up period

 Martínez, 2016 [16]

20

80

20

5

1

3

4

12

30 days

 Venugopal, 2019 [23]

66.7

77.3

62

9

6

12

3

41

NA

  1. Abbreviation: AUROC area under the receiver operating characteristics, AKI acute kidney injury, FN false negative, FP false positive, NA not applicable, RRT renal replacement therapy, TN true negative, TP true positive