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Table 4 Bacteremia count data

From: Structural equation modeling the “control of gut overgrowth” in the prevention of ICU-acquired Gram-negative infection

 

Observational studies

Infection prevention studies

 

No intervention

Non-dec

Anti-septic

TAP ± PPAP

All groups

Acinetobacter

  CC or observational groups

203/189338

0.11% (20)

1/553

0.18% (2)

17/39162

0.04% (8)

15/1860

0.8% (13)

  Intervention groups

 

1/526

0.19% (2)

7/57009

0.01% (8)

15/13290a

0.11% (18)

Pseudomonas

  CC or observational groups

567/192203

0.30% (27)

2/553

0.36% (2)

23/39162

0.06% (8)

63/5280

1.2% (16)

  Intervention groups

 

3/526

0.57% (2)

52/59117

0.09% (9)

139/23543

0.59% (25)

Excluding groups with LOS < 7 days

Acinetobacter

  CC or observational groups

37/12913b,c

0.29% (11)

0/200b

0% (1)

0/308b

0% (3)

14/904b

1.5% (11)

  Intervention groups

 

1/199c

0.5% (1)

1/305c

0.33% (3)

11/1256c

0.88% (14)

Pseudomonas

  CC or observational groups

111/14453d,e

0.77% (16)

0/200d

0% (1)

0/308d

0.0% (3)

63/5249d

1.2% (15)

  Intervention groups

 

2/199e

1.0% (1)

17/2413e

0.7% (4)

94/12531e,f

0.75% (22)

  1. Non-dec non-decontamination studies, TAP topical antibiotic prophylaxis, PPAP protocolized parenteral antibiotic prophylaxis.
  2. aAmong intervention groups of TAP-based prevention studies, the count of Acinetobacter bacteremias was 12/6609 (0.18%; 13 studies) versus 3/6681 (0.04%; 4 studies) for those using versus not including PPAP in the intervention (p = 0.02; Fisher’s exact test)
  3. bThe counts of Acinetobacter bacteremias among the three categories of control groups and the category of observation groups among studies after excluding those with length of stay < 7 days differed significantly (p < 0.001; Fisher’s exact test)
  4. cThe counts of Acinetobacter bacteremias among the three categories of intervention groups and the category of observation groups among studies after excluding those with length of stay < 7 days differed significantly (p = 0.012; Fisher’s exact test)
  5. dThe counts of Pseudomonas bacteremias among the three categories of control groups and the category of observation groups among studies after excluding those with length of stay < 7 days differed significantly (p = 0.010; Fisher’s exact test)
  6. eThe counts of Pseudomonas bacteremias among the three categories of intervention groups and the category of observation groups among studies after excluding those with length of stay < 7 days were not significantly different (p = 0.90; Fisher’s exact test)
  7. fAmong intervention groups of TAP-based prevention studies excluding those with a LOS less than 7 days, the count of Pseudomonas bacteremias was 53/5908 (0.9%; 16 studies) versus 41/6623 (0.62%; 6 studies) for those using versus not including PPAP in the intervention (p = 0.07; Fisher’s exact test)