Skip to main content

Table 4 Bacteremia count data

From: Structural equation modeling the “control of gut overgrowth” in the prevention of ICU-acquired Gram-negative infection

 Observational studiesInfection prevention studies 
No interventionNon-decAnti-septicTAP ± PPAP
All groups
Acinetobacter
  CC or observational groups203/189338
0.11% (20)
1/553
0.18% (2)
17/39162
0.04% (8)
15/1860
0.8% (13)
  Intervention groups 1/526
0.19% (2)
7/57009
0.01% (8)
15/13290a
0.11% (18)
Pseudomonas
  CC or observational groups567/192203
0.30% (27)
2/553
0.36% (2)
23/39162
0.06% (8)
63/5280
1.2% (16)
  Intervention groups 3/526
0.57% (2)
52/59117
0.09% (9)
139/23543
0.59% (25)
Excluding groups with LOS < 7 days
Acinetobacter
  CC or observational groups37/12913b,c
0.29% (11)
0/200b
0% (1)
0/308b
0% (3)
14/904b
1.5% (11)
  Intervention groups 1/199c
0.5% (1)
1/305c
0.33% (3)
11/1256c
0.88% (14)
Pseudomonas
  CC or observational groups111/14453d,e
0.77% (16)
0/200d
0% (1)
0/308d
0.0% (3)
63/5249d
1.2% (15)
  Intervention groups 2/199e
1.0% (1)
17/2413e
0.7% (4)
94/12531e,f
0.75% (22)
  1. Non-dec non-decontamination studies, TAP topical antibiotic prophylaxis, PPAP protocolized parenteral antibiotic prophylaxis.
  2. aAmong intervention groups of TAP-based prevention studies, the count of Acinetobacter bacteremias was 12/6609 (0.18%; 13 studies) versus 3/6681 (0.04%; 4 studies) for those using versus not including PPAP in the intervention (p = 0.02; Fisher’s exact test)
  3. bThe counts of Acinetobacter bacteremias among the three categories of control groups and the category of observation groups among studies after excluding those with length of stay < 7 days differed significantly (p < 0.001; Fisher’s exact test)
  4. cThe counts of Acinetobacter bacteremias among the three categories of intervention groups and the category of observation groups among studies after excluding those with length of stay < 7 days differed significantly (p = 0.012; Fisher’s exact test)
  5. dThe counts of Pseudomonas bacteremias among the three categories of control groups and the category of observation groups among studies after excluding those with length of stay < 7 days differed significantly (p = 0.010; Fisher’s exact test)
  6. eThe counts of Pseudomonas bacteremias among the three categories of intervention groups and the category of observation groups among studies after excluding those with length of stay < 7 days were not significantly different (p = 0.90; Fisher’s exact test)
  7. fAmong intervention groups of TAP-based prevention studies excluding those with a LOS less than 7 days, the count of Pseudomonas bacteremias was 53/5908 (0.9%; 16 studies) versus 41/6623 (0.62%; 6 studies) for those using versus not including PPAP in the intervention (p = 0.07; Fisher’s exact test)