Normal range | Total (n = 107) | Survivors (n = 88) | Non-survivors (n = 19) | P value | |
---|---|---|---|---|---|
White blood cell count, × 109/L | 3.5–9.5 | 4.6 (3.7–6.1) | 4.4 (3.4–5.8) | 6.7 (4.6–10.3) | 0.004* |
Neutrophil count, × 109/L | 1.8–6.3 | 3.1 (2.1–4.7) | 2.8 (2.0–3.9) | 5.4 (3.2–8.5) | < 0.001* |
Lymphocyte count, × 109/L | 1.1–3.2 | 0.9 (0.7–1.2) | 0.9 (0.7–1.3) | 0.8 (0.5–1.1) | 0.121 |
Platelet count, × 109/L | 125–350 | 175 (129–200) | 178 (139–207) | 122 (83–178) | 0.006* |
Prothrombin time, s | 9.4–12.5 | 12.8 (11.9–13.5) | 12.9 (12.0–13.5) | 12.6 (11.9–13.5) | 0.813 |
Activated partial thromboplastin time, s | 25.1–36.5 | 31.7 (29.4–33.9) | 31.7 (29.5–33.5) | 32.7 (27.5–37.0) | 0.850 |
D-dimer, mg/L | 0–500 | 203 (121–358) | 191 (108–327) | 439 (202–1991) | 0.003* |
Creatine kinase, U/L | < 171 | 90 (54–138) | 86 (53–121) | 142 (87–325) | 0.022* |
Creatine kinase-MB, U/L | < 25 | 14 (10–18) | 13 (9–16) | 18 (13–44) | 0.008* |
Lactate dehydrogenase, U/L | 125–243 | 236 (176–369) | 227 (171–329) | 456 (254–588) | 0.010* |
Alanine aminotransferase, U/L | 9–50 | 23 (16–39) | 22 (15–34) | 47 (22–66) | 0.002* |
Aspartate aminotransferase, U/L | 15–40 | 31 (24–47) | 29 (23–41) | 67 (38–90) | < 0.001* |
Total bilirubin, mmol/L | 5–21 | 9.8 (8.4–14.1) | 9.5 (8.4–12.9) | 11.3 (9.4–20.7) | 0.069 |
Blood urea nitrogen, mmol/L | 2.8–7.6 | 4.2 (3.2–5.6) | 3.9 (3.0–4.7) | 6.1 (4.9–10.5) | < 0.001* |
Creatinine, μmol/L | 64–104 | 71 (60–86) | 68 (58–83) | 87 (71–130) | < 0.001* |
Hypersensitive troponin I, > 26.2 pg/mL, no. (%) | < 26.2 | 6 (5.6) | 1 (1.1) | 5 (26.3) | 0.001* |
Multi-lobar involvement on initial radiographs, no. (%) | NA | 90 (84.1) | 73 (83.0) | 17 (89.5) | 0.731 |
Bilateral involvement on radiographs during hospitalization, no. (%) | NA | 105 (98.1) | 86 (97.7) | 19 (100.0) | 1.000 |