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Table 1 Patients characteristics

From: Circulating dipeptidyl peptidase-3 at admission is associated with circulatory failure, acute kidney injury and death in severely ill burn patients

Patient’s characteristics

Total, N = 111

90-day survivors, N = 75

90-day non-survivors, N = 36

p

Sex, male—n (%)

71 (64)

51 (68)

20 (56)

0.2858

Age—year

48 [32.5–63]

42 [29–58]

56.5 [42–79]

0.0013

BMI—kg/m2

25.2 [22.9–28.7]

25.1 [23–28.3]

25.7 [22.4–29.1]

0.9673

Medical history

 CIC—n (%)

3 (2.7)

2 (3)

1 (3)

1.0000

 COPD—n (%)

3 (2.7)

2 (3)

1 (3)

1.0000

 CKD—n (n)

5 (4.5)

1 (1)

4 (11)

0.0374

 Chronic HBP—n (%)

25 (22.5)

12 (16)

13 (36)

0.0277

 Psychiatric—n (%)

34 (30.6)

22 (29)

12 (33)

0.6668

Burn characteristics

 TBSA—%

35 [25–53.5]

32 [22–45]

57 [31–70]

< 0.0001

 Deep burn BSA—%

21 [10–40]

17 [7–30]

42 [15–61]

0.0001

 Inhalation injury—n (%)

54 (48.6)

28 (37)

26 (72)

0.0012

Characteristics during hospitalization

 Mechanic ventilation—n (%)

82 (73.9)

52 (69)

30 (83)

0.1799

 DPP3admin (ng/mL)

30.6 [22.4–53.6]

27.1 [19.4–40.2]

53.3 [29.5–104]

< 0.0001

 DPP3day3 (ng/mL)

17.3 [11.8–25.2]

14.1 [11.5–20.6]

22.1 [16.6–30.8]

0.0102

 Screat—μmol/L

72.5 [56.5–92]

70 [54.8–81.3]

90.5 [67.3–138.3]

0.0003

 Lactate—mmol/L

3.5 [2.0–5.7]

2.7 [1.7–4.6]

5.2 [3.5–8]

< 0.0001

 Bilirubin—mmol/L

14.0 [9.3–21.3]

12.9 [9–19.3]

18 [10.9–25.9]

0.0945

 Platelet—G/L

250 [185–304]

236 [183–277]

279 [180–372]

0.3840

 Length of hospitalization—days

90 [35.5–90]

41 [26–61]

18 [2–32.5]

< 0.0001

 RRT—n (%)

24 (21.6)

5 (7)

28 (78)

< 0.0001

Severity scores

 SOFA

4 [1–7]

2 [0–4]

6.5 [3.3–9.8]

< 0.0001

 ABSI

8 [7–11]

8 [6–9]

11 [9–13]

< 0.0001

 SAPS2

33 [23–47]

28 [20–42]

47 [33–62]

< 0.0001

 UBS

100 [52.5–166]

84 [45–132]

184 [86–249]

< 0.0001

Hemodynamic on admission

 Echocardiography, n (%)

59 (53)

33 (44)

26 (72)

0.0078

 Systolic cardiac dysfunction, n (%)

10 (9)

2 (3)

8 (22)

0.0163

 Circulatory failure, n (%)

53 (48)

24 (32)

29 (81)

< 0.0001

 MAP in mmHg

79 [70–95]

84 [73–97]

73 [64–85]

0.0104

 Volume of crystalloids at day 1

8250 [3700–15,000]

6700 [3300–12,800]

13,400 [6430–18,380]

0.0018

 Volume of crystalloids at day 2

3000 [1000–5650]

2500 [1000–5150]

4000 [2000–7500]

0.1078

  1. BMI body mass index, CIC chronic ischemic cardiopathy, COPD chronic obstructive pulmonary disease, CKD chronic kidney disease, HBP high blood pressure, TBSA total burn surface area, ECMO extracorporeal membrane oxygenation, Screat serum creatinine at admission, RRT renal replacement therapy, SOFA score simplified organ failure assessment, ABSI Abbreviated Burn Severity Index, UBS Unit Burn Standard, SAPS 2 The Simplified Acute Physiology Score
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