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Table 1 Patients characteristics

From: Circulating dipeptidyl peptidase-3 at admission is associated with circulatory failure, acute kidney injury and death in severely ill burn patients

Patient’s characteristicsTotal, N = 11190-day survivors, N = 7590-day non-survivors, N = 36p
Sex, male—n (%)71 (64)51 (68)20 (56)0.2858
Age—year48 [32.5–63]42 [29–58]56.5 [42–79]0.0013
BMI—kg/m225.2 [22.9–28.7]25.1 [23–28.3]25.7 [22.4–29.1]0.9673
Medical history
 CIC—n (%)3 (2.7)2 (3)1 (3)1.0000
 COPD—n (%)3 (2.7)2 (3)1 (3)1.0000
 CKD—n (n)5 (4.5)1 (1)4 (11)0.0374
 Chronic HBP—n (%)25 (22.5)12 (16)13 (36)0.0277
 Psychiatric—n (%)34 (30.6)22 (29)12 (33)0.6668
Burn characteristics
 TBSA—%35 [25–53.5]32 [22–45]57 [31–70]< 0.0001
 Deep burn BSA—%21 [10–40]17 [7–30]42 [15–61]0.0001
 Inhalation injury—n (%)54 (48.6)28 (37)26 (72)0.0012
Characteristics during hospitalization
 Mechanic ventilation—n (%)82 (73.9)52 (69)30 (83)0.1799
 DPP3admin (ng/mL)30.6 [22.4–53.6]27.1 [19.4–40.2]53.3 [29.5–104]< 0.0001
 DPP3day3 (ng/mL)17.3 [11.8–25.2]14.1 [11.5–20.6]22.1 [16.6–30.8]0.0102
 Screat—μmol/L72.5 [56.5–92]70 [54.8–81.3]90.5 [67.3–138.3]0.0003
 Lactate—mmol/L3.5 [2.0–5.7]2.7 [1.7–4.6]5.2 [3.5–8]< 0.0001
 Bilirubin—mmol/L14.0 [9.3–21.3]12.9 [9–19.3]18 [10.9–25.9]0.0945
 Platelet—G/L250 [185–304]236 [183–277]279 [180–372]0.3840
 Length of hospitalization—days90 [35.5–90]41 [26–61]18 [2–32.5]< 0.0001
 RRT—n (%)24 (21.6)5 (7)28 (78)< 0.0001
Severity scores
 SOFA4 [1–7]2 [0–4]6.5 [3.3–9.8]< 0.0001
 ABSI8 [7–11]8 [6–9]11 [9–13]< 0.0001
 SAPS233 [23–47]28 [20–42]47 [33–62]< 0.0001
 UBS100 [52.5–166]84 [45–132]184 [86–249]< 0.0001
Hemodynamic on admission
 Echocardiography, n (%)59 (53)33 (44)26 (72)0.0078
 Systolic cardiac dysfunction, n (%)10 (9)2 (3)8 (22)0.0163
 Circulatory failure, n (%)53 (48)24 (32)29 (81)< 0.0001
 MAP in mmHg79 [70–95]84 [73–97]73 [64–85]0.0104
 Volume of crystalloids at day 18250 [3700–15,000]6700 [3300–12,800]13,400 [6430–18,380]0.0018
 Volume of crystalloids at day 23000 [1000–5650]2500 [1000–5150]4000 [2000–7500]0.1078
  1. BMI body mass index, CIC chronic ischemic cardiopathy, COPD chronic obstructive pulmonary disease, CKD chronic kidney disease, HBP high blood pressure, TBSA total burn surface area, ECMO extracorporeal membrane oxygenation, Screat serum creatinine at admission, RRT renal replacement therapy, SOFA score simplified organ failure assessment, ABSI Abbreviated Burn Severity Index, UBS Unit Burn Standard, SAPS 2 The Simplified Acute Physiology Score