TY - JOUR AU - Fowler, A. A. AU - Truwit, J. D. AU - Hite, R. D. AU - Morris, P. E. AU - DeWilde, C. AU - Priday, A. PY - 2019 DA - 2019// TI - Effect of vitamin C infusion on organ failure and biomarkers of inflammation and vascular injury in patients with sepsis and severe acute respiratory failure: the CITRIS-ALI randomized clinical trial JO - JAMA. VL - 322 UR - https://doi.org/10.1001/jama.2019.11825 DO - 10.1001/jama.2019.11825 ID - Fowler2019 ER - TY - JOUR AU - Marik, P. E. AU - Khangoora, V. AU - Rivera, R. AU - Hooper, M. H. AU - Catravas, J. PY - 2017 DA - 2017// TI - Hydrocortisone, vitamin C, and thiamine for the treatment of severe sepsis and septic shock: a retrospective before-after study JO - Chest. VL - 151 UR - https://doi.org/10.1016/j.chest.2016.11.036 DO - 10.1016/j.chest.2016.11.036 ID - Marik2017 ER - TY - JOUR AU - Padayatty, S. J. AU - Levine, M. PY - 2016 DA - 2016// TI - Vitamin C: the known and the unknown and Goldilocks JO - Oral Dis VL - 22 UR - https://doi.org/10.1111/odi.12446 DO - 10.1111/odi.12446 ID - Padayatty2016 ER - TY - JOUR AU - Hooper, M. H. AU - Carr, A. AU - Marik, P. E. PY - 2019 DA - 2019// TI - The adrenal-vitamin C axis: from fish to guinea pigs and primates JO - Crit Care VL - 23 UR - https://doi.org/10.1186/s13054-019-2332-x DO - 10.1186/s13054-019-2332-x ID - Hooper2019 ER - TY - JOUR AU - Carr, A. C. AU - Rosengrave, P. C. AU - Bayer, S. AU - Chambers, S. AU - Mehrtens, J. AU - Shaw, G. M. PY - 2017 DA - 2017// TI - Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes JO - Crit Care VL - 21 UR - https://doi.org/10.1186/s13054-017-1891-y DO - 10.1186/s13054-017-1891-y ID - Carr2017 ER - TY - JOUR AU - Jackson, T. S. AU - Xu, A. AU - Vita, J. A. AU - Keaney, J. F. PY - 1998 DA - 1998// TI - Ascorbate prevents the interaction of superoxide and nitric oxide only at very high physiological concentrations JO - Circ Res VL - 83 UR - https://doi.org/10.1161/01.RES.83.9.916 DO - 10.1161/01.RES.83.9.916 ID - Jackson1998 ER - TY - JOUR AU - Grooth, H. J. AU - Manubulu-Choo, W. P. AU - Zandvliet, A. S. AU - Spoelstra-de Man, A. M. E. AU - Girbes, A. R. AU - Swart, E. L. PY - 2018 DA - 2018// TI - Vitamin C pharmacokinetics in critically ill patients: a randomized trial of four IV regimens JO - Chest. VL - 153 UR - https://doi.org/10.1016/j.chest.2018.02.025 DO - 10.1016/j.chest.2018.02.025 ID - Grooth2018 ER - TY - JOUR AU - Wang, Y. AU - Lin, H. AU - Lin, B. W. AU - Lin, J. D. PY - 2019 DA - 2019// TI - Effects of different ascorbic acid doses on the mortality of critically ill patients: a meta-analysis JO - Ann Intensive Care VL - 9 UR - https://doi.org/10.1186/s13613-019-0532-9 DO - 10.1186/s13613-019-0532-9 ID - Wang2019 ER - TY - JOUR AU - Cruickshank, A. M. AU - Telfer, A. B. AU - Shenkin, A. PY - 1988 DA - 1988// TI - Thiamine deficiency in the critically ill JO - Intensive Care Med VL - 14 UR - https://doi.org/10.1007/BF00262893 DO - 10.1007/BF00262893 ID - Cruickshank1988 ER - TY - JOUR AU - Moskowitz, A. AU - Andersen, L. W. AU - Cocchi, M. N. AU - Karlsson, M. AU - Patel, P. V. AU - Donnino, M. W. PY - 2017 DA - 2017// TI - Thiamine as a renal protective agent in septic shock. A secondary analysis of a randomized, double-blind, placebo-controlled trial JO - Ann Am Thorac Soc VL - 14 UR - https://doi.org/10.1513/AnnalsATS.201608-656BC DO - 10.1513/AnnalsATS.201608-656BC ID - Moskowitz2017 ER - TY - JOUR AU - Moskowitz, A. AU - Andersen, L. W. AU - Huang, D. T. AU - Berg, K. M. AU - Grossestreuer, A. V. AU - Marik, P. E. PY - 2018 DA - 2018// TI - Ascorbic acid, corticosteroids, and thiamine in sepsis: a review of the biologic rationale and the present state of clinical evaluation JO - Crit Care VL - 22 UR - https://doi.org/10.1186/s13054-018-2217-4 DO - 10.1186/s13054-018-2217-4 ID - Moskowitz2018 ER - TY - JOUR AU - Barabutis, N. AU - Khangoora, V. AU - Marik, P. E. AU - Catravas, J. D. PY - 2017 DA - 2017// TI - Hydrocortisone and ascorbic acid synergistically prevent and repair lipopolysaccharide-induced pulmonary endothelial barrier dysfunction JO - Chest. VL - 152 UR - https://doi.org/10.1016/j.chest.2017.07.014 DO - 10.1016/j.chest.2017.07.014 ID - Barabutis2017 ER - TY - STD TI - Sadaka F, Grady J, Organti N, Donepudi B, Korobey M, Tannehill D, et al. Ascorbic acid, thiamine, and steroids in septic shock: propensity matched analysis. J Intensive Care Med. 2019;885066619864541:1–5. ID - ref13 ER - TY - JOUR AU - Kim, W. Y. AU - Jo, E. J. AU - Eom, J. S. AU - Mok, J. AU - Kim, M. H. AU - Kim, K. U. PY - 2018 DA - 2018// TI - Combined vitamin C, hydrocortisone, and thiamine therapy for patients with severe pneumonia who were admitted to the intensive care unit: propensity score-based analysis of a before-after cohort study JO - J Crit Care VL - 47 UR - https://doi.org/10.1016/j.jcrc.2018.07.004 DO - 10.1016/j.jcrc.2018.07.004 ID - Kim2018 ER - TY - STD TI - Litwak JJ, Cho N, Nguyen HB, Moussavi K, Bushell T. Vitamin C, Hydrocortisone, and thiamine for the treatment of severe sepsis and septic shock: a retrospective analysis of real-world application. J Clin Med. 2019;8(4):478. ID - ref15 ER -