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Table 1 Summary of the clinical characteristics of the 66 aSAH patients

From: Lasting s-ketamine block of spreading depolarizations in subarachnoid hemorrhage: a retrospective cohort study

 No s-ketamines-ketaminep value
Number of patients3333 
Male9150.125
Age55.8 ± 11.751.1 ± 8.00.064
MAP (mmHg)95.8 ± 16.3100.7 ± 8.10.125
ICP (mmHg)13.1 ± 15.011.2 ± 4.10.500
CPP (mmHg)83.0 ± 28.289.6 ± 8.90.219
Pneumonia16200.323
Urinary tract infection640.492
Monitoring days14.8 ± 4.917.0 ± 2.30.024
AcoA9130.649
ACoP21 
BCA01 
ICA33 
MCA1815 
PericA10 
Aneurysm diameter7.5 ± 5.17.3 ± 4.40.864
WFNS1320.405
272 
333 
4711 
51315 
Modified Fisher Scale0000.198
110
210
3105
42128
ICH 10120.763
No ICH2321
InfarctionAreal20210.683
Lacunar43
No99
eGOS1780.154
202
376
458
526
631
741
841
  1. Neuroimaging was performed following standard care when clinical deterioration was noted. No strict imaging protocol was established for the purpose of the study. Therefore, caution is warranted in the interpretation of the imaging results. CT and/or magnetic resonance imaging (MRI) scans were analyzed to identify focal lesions (infarct or hemorrhage). VK analyzed the neuroimages blinded to the clinical courses and ECoG analyses. An infarct with a diameter ≤ 15 mm was denoted as “lacunar.” An infarct > 15 mm was denoted as “areal.” Hyperintensities in diffusion-weighted imaging (DWI) or hypodensities on CT resulting from ventricular catheters or intraparenchymal hematoma were documented as such. Intracerebral hemorrhages (ICH) appeared hypodense on later CT scans. These hypodensities as well as peri-hematomal hypodensities were denoted as “ICH” and not rated as ischemic lesions. All ICHs occurred during the initial hemorrhage. By contrast, ischemic infarcts could occur early or in a delayed fashion. The table reports whether patients developed an ischemic infarct at any time during the clinical course after the hemorrhage. Welch’s t-tests or chi-squared tests were applied as appropriate. ACoA anterior communicating artery, ACoP posterior communicating artery, BCA basilar cerebral artery, ICA internal carotid artery, MCA middle cerebral artery, PericA pericallosal artery, WNFS World Federation of Neurosurgical Societies Sheart scale, eGOS extended Glasgow Outcome Scale