Fig. 4

Development of multiple variables over time in patients with aSAH who received s-ketamine at any time during the monitoring versus patients who did not. Patients treated with s-ketamine also received higher doses of the other sedatives and analgesics. Accordingly, also CRP was higher which might reflect a higher rate of infections under sedation. The time courses illustrate the selection bias of the study with patients requiring s-ketamine at any time during the monitoring having more severe aSAH. The means are presented here with 95% confidence interval (CI)