From: Driving pressure is not associated with mortality in mechanically ventilated patients without ARDS
Analysis | Group | Outcome | Exposure | OR (95% CI) | p | pFDR |
---|---|---|---|---|---|---|
Primary | Non-ARDS | 30-day mortality | Driving pressure | 1.02 (0.97 to 1.06) | 0.463 | |
Secondary | Non-ARDS | 30-day mortality | Tidal volume | 1.22 (1.07 to 1.39) | 0.003 | 0.01 |
Secondary | Non-ARDS | 30-day mortality | Compliance | > 1 (0.99 to 1.01) | 0.890 | 0.89 |
Confirmatory | ARDS | 30-day mortality | Driving pressure | 1.1 (1.06 to 1.14) | < 0.001 | < 0.001 |
Confirmatory | ARDS | 30-day mortality | Tidal volume | 1.17 (1.04 to 1.31) | 0.007 | 0.015 |
Confirmatory | ARDS | 30-day mortality | Compliance | < 1 (0.99 to > 1) | 0.314 | 0.472 |