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Table 1 Baseline patient characteristics before and after propensity score matching (10 g minimum threshold of high-dose vitamin C)

From: Effect of high-dose vitamin C therapy on severe burn patients: a nationwide cohort study

VariablesBefore propensity score matchingAfter propensity score matching
High-dose vitamin C group (n = 157)Control group (n = 2556)Standardized difference (%)High-dose vitamin C group (n = 157)Control group (n = 628)Standardized difference (%)
Age(years), median (IQR)67 (48–80)69 (51–80)11.767 (48–80)67.5 (50–80)7.6
Male, n (%)87 (55.4)1561 (61.1)11.587 (55.4)332 (52.9)5.1
Body weight (Kg), median (IQR)58.5 (47.4–68.9)55.4 (45–65)23.458.5 (47.4–68.9)57.15 (50–69)2.6
Burn index, median (IQR)34 (24–50)25 (18–40)39.334 (24–50)34.5 (23–53.4)1.1
Inhalation injury, n (%)45 (28.7)523 (20.5)19.145 (28.7)181 (28.8)0.4
Charlson comorbidity Index, n (%)
 0 (low)126 (80.3)1917 (75.0)12.6126 (80.3)484 (77.1)7.8
 1 (medium)24 (15.3)444 (17.4)5.624 (15.3)115 (18.3)8.1
 ≥ 2 (high)7 (4.5)195 (7.6)13.37 (4.59)29 (4.6)0.8
Japan Coma Scale, n (%)
 0 (alert)69 (43.9)1406 (55.0)22.369 (43.9)266 (42.4)3.2
 1–30 (dizziness)38 (24.2)553 (21.6)6.138 (24.2)145 (23.1)2.6
 10–30 (somnolence)6 (3.8)173 (6.8)13.26 (3.8)28 (4.5)3.2
 100–300 (coma)44 (28.0)424 (16.6)27.744 (28.0)189 (30.1)4.6
Prescriptions within 1 day, n (%)
 Vasopressor use44 (28.0)441 (17.3)25.944 (28.0)180 (28.7)1.4
 Albumin use74 (47.1)530 (20.7)57.974 (47.1)285 (45.4)3.5
 Hydroxyethyl starch use13 (8.3)122 (4.8)14.213 (8.3)43 (6.8)5.4
 Intravenous antibiotics use70 (44.6)1159 (45.3)1.570 (44.6)289 (46.0)2.9
 Neuromuscular blockade use63 (40.1)565 (22.1)39.663 (40.1)254 (40.4)0.6
 Haptoglobin use59 (37.6)378 (14.8)53.659 (37.6)242 (38.5)2.0
 Transfusion use34 (21.7)212 (8.3)38.034 (21.7)132 (21.0)1.6
Procedures within 1 day, n (%)
 Operation61 (38.9)438 (17.1)49.761 (38.9)243 (38.7)0.3
 Mechanical ventilation114 (72.6)1180 (46.2)55.8114 (72.6)474 (75.5)6.5
 Renal replacement therapy8 (5.1)71 (2.8)11.98 (5.1)27 (4.3)3.8
 Endoscopy54 (34.4)448 (17.5)39.154 (34.4)212 (33.8)1.3
 Enteral feeding11 (7.0)202 (7.9)3.411 (7.0)47 (7.5)1.8
 Intra-arterial blood pressure monitoring123 (78.3)1161 (45.4)71.9123 (78.3)492 (78.3)0.1
Admission site, n (%)
 Teaching hospital156 (99.4)2436 (95.3)25.4156 (99.4)623 (99.2)1.9
 Intensive care unit155 (98.7)2059 (80.6)62.4155 (98.7)622 (99.0)3.0
Transportation from another hospital, n (%)7 (4.5)124 (4.9)1.97 (4.5)35 (5.6)5.1
  1. IQR interquartile range