Table 1 Baseline patient characteristics before and after propensity score matching (10 g minimum threshold of high-dose vitamin C)
From: Effect of high-dose vitamin C therapy on severe burn patients: a nationwide cohort study
Variables | Before propensity score matching | After propensity score matching | ||||
|---|---|---|---|---|---|---|
High-dose vitamin C group (n = 157) | Control group (n = 2556) | Standardized difference (%) | High-dose vitamin C group (n = 157) | Control group (n = 628) | Standardized difference (%) | |
Age(years), median (IQR) | 67 (48–80) | 69 (51–80) | 11.7 | 67 (48–80) | 67.5 (50–80) | 7.6 |
Male, n (%) | 87 (55.4) | 1561 (61.1) | 11.5 | 87 (55.4) | 332 (52.9) | 5.1 |
Body weight (Kg), median (IQR) | 58.5 (47.4–68.9) | 55.4 (45–65) | 23.4 | 58.5 (47.4–68.9) | 57.15 (50–69) | 2.6 |
Burn index, median (IQR) | 34 (24–50) | 25 (18–40) | 39.3 | 34 (24–50) | 34.5 (23–53.4) | 1.1 |
Inhalation injury, n (%) | 45 (28.7) | 523 (20.5) | 19.1 | 45 (28.7) | 181 (28.8) | 0.4 |
Charlson comorbidity Index, n (%) | ||||||
0 (low) | 126 (80.3) | 1917 (75.0) | 12.6 | 126 (80.3) | 484 (77.1) | 7.8 |
1 (medium) | 24 (15.3) | 444 (17.4) | 5.6 | 24 (15.3) | 115 (18.3) | 8.1 |
≥ 2 (high) | 7 (4.5) | 195 (7.6) | 13.3 | 7 (4.59) | 29 (4.6) | 0.8 |
Japan Coma Scale, n (%) | ||||||
0 (alert) | 69 (43.9) | 1406 (55.0) | 22.3 | 69 (43.9) | 266 (42.4) | 3.2 |
1–30 (dizziness) | 38 (24.2) | 553 (21.6) | 6.1 | 38 (24.2) | 145 (23.1) | 2.6 |
10–30 (somnolence) | 6 (3.8) | 173 (6.8) | 13.2 | 6 (3.8) | 28 (4.5) | 3.2 |
100–300 (coma) | 44 (28.0) | 424 (16.6) | 27.7 | 44 (28.0) | 189 (30.1) | 4.6 |
Prescriptions within 1 day, n (%) | ||||||
Vasopressor use | 44 (28.0) | 441 (17.3) | 25.9 | 44 (28.0) | 180 (28.7) | 1.4 |
Albumin use | 74 (47.1) | 530 (20.7) | 57.9 | 74 (47.1) | 285 (45.4) | 3.5 |
Hydroxyethyl starch use | 13 (8.3) | 122 (4.8) | 14.2 | 13 (8.3) | 43 (6.8) | 5.4 |
Intravenous antibiotics use | 70 (44.6) | 1159 (45.3) | 1.5 | 70 (44.6) | 289 (46.0) | 2.9 |
Neuromuscular blockade use | 63 (40.1) | 565 (22.1) | 39.6 | 63 (40.1) | 254 (40.4) | 0.6 |
Haptoglobin use | 59 (37.6) | 378 (14.8) | 53.6 | 59 (37.6) | 242 (38.5) | 2.0 |
Transfusion use | 34 (21.7) | 212 (8.3) | 38.0 | 34 (21.7) | 132 (21.0) | 1.6 |
Procedures within 1 day, n (%) | ||||||
Operation | 61 (38.9) | 438 (17.1) | 49.7 | 61 (38.9) | 243 (38.7) | 0.3 |
Mechanical ventilation | 114 (72.6) | 1180 (46.2) | 55.8 | 114 (72.6) | 474 (75.5) | 6.5 |
Renal replacement therapy | 8 (5.1) | 71 (2.8) | 11.9 | 8 (5.1) | 27 (4.3) | 3.8 |
Endoscopy | 54 (34.4) | 448 (17.5) | 39.1 | 54 (34.4) | 212 (33.8) | 1.3 |
Enteral feeding | 11 (7.0) | 202 (7.9) | 3.4 | 11 (7.0) | 47 (7.5) | 1.8 |
Intra-arterial blood pressure monitoring | 123 (78.3) | 1161 (45.4) | 71.9 | 123 (78.3) | 492 (78.3) | 0.1 |
Admission site, n (%) | ||||||
Teaching hospital | 156 (99.4) | 2436 (95.3) | 25.4 | 156 (99.4) | 623 (99.2) | 1.9 |
Intensive care unit | 155 (98.7) | 2059 (80.6) | 62.4 | 155 (98.7) | 622 (99.0) | 3.0 |
Transportation from another hospital, n (%) | 7 (4.5) | 124 (4.9) | 1.9 | 7 (4.5) | 35 (5.6) | 5.1 |