Table 1 Baseline characteristics of study groups
Characteristics | Plasma-Lyte-A (n = 34) | 0.9% saline (n = 32) | P value |
|---|---|---|---|
Age in years | 7.8 (4.0, 11.6) | 6.6 (2.9, 10.1) | 0.305 |
Male gender, n (%) | 18 (52.9) | 15 (46.9) | 0.622 |
Weight for age (z score) | − 2.9 (− 3.18, − 1.13) | − 1.8 (− 2.77, − 0.67) | 0.197 |
Height for age (z score)) | − 1.25 (− 2.58, − 0.78) | − 1.32 (− 1.90, − 0.52) | 0.441 |
BMI for age (z score) | − 1.79 (− 2.93, − 0.77) | − 1.5 (− 3.0, − 0.77) | 0.99 |
Socioeconomic class* | 3 (3, 4) | 3 (3, 4) | 0.481 |
New onset DKA, n (%) | 17 (50) | 24 (75) | 0.03 |
Duration of diabetes in known type 1 diabetes (months) | 26.7 (7.2, 47.8) | 15.4 (6.1, 32.2) | 0.861 |
Age of onset of diabetes (months) | 79.5 (46.8, 99.7) | 79.7 (31.6, 109.6) | 0.857 |
Previous episode of DKA, n (%) | |||
None | 23 (67.6) | 25 (78.1) | |
≤ 2 | 10 (29.4) | 6 (18.8) | |
> 2 | 1 (3.0) | 1 (3.1) | |
Type of insulin regimen, n (%) | |||
Basal bolus | 13 (76.5) | 8 (100) | 0.134 |
Spilt mix | 4 (23.5) | 0 (0) | |
Poor compliance to insulin, n (%) | 13 (76.5) | 8 (100) | 0.134 |
Time from onset of symptoms to presentation (days) | 4 (2.0, 7.7) | 6 (3, 10) | 0.23 |
Severity of DKA, n (%) | |||
Severe | 20 (58.8) | 20 (62.5) | 0.95 |
Moderate | 11 (32.4) | 11 (34.4) | 0.62 |
Mild | 3 (8.8) | 1 (3.1) | 0.13 |
GCS at admission | 14 (11, 15) | 13 (10, 15) | 0.547 |
Hypotension at admission, n (%) | 2 (5.9) | 2 (6.3) | 0.95 |
Need for PICU, n (%) | 21 (61.8) | 14 (43.8) | 0.143 |