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Table 1 Baseline characteristics of study groups

From: 0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial

CharacteristicsPlasma-Lyte-A (n = 34)0.9% saline (n = 32)P value
Age in years7.8 (4.0, 11.6)6.6 (2.9, 10.1)0.305
Male gender, n (%)18 (52.9)15 (46.9)0.622
Weight for age (z score)− 2.9 (− 3.18, − 1.13)− 1.8 (− 2.77, − 0.67)0.197
Height for age (z score))− 1.25 (− 2.58, − 0.78)− 1.32 (− 1.90, − 0.52)0.441
BMI for age (z score)− 1.79 (− 2.93, − 0.77)− 1.5 (− 3.0, − 0.77)0.99
Socioeconomic class*3 (3, 4)3 (3, 4)0.481
New onset DKA, n (%)17 (50)24 (75)0.03
Duration of diabetes in known type 1 diabetes (months)26.7 (7.2, 47.8)15.4 (6.1, 32.2)0.861
Age of onset of diabetes (months)79.5 (46.8, 99.7)79.7 (31.6, 109.6)0.857
Previous episode of DKA, n (%)
 None23 (67.6)25 (78.1) 
 ≤ 210 (29.4)6 (18.8) 
 > 21 (3.0)1 (3.1) 
Type of insulin regimen, n (%)
 Basal bolus13 (76.5)8 (100)0.134
 Spilt mix4 (23.5)0 (0) 
Poor compliance to insulin, n (%)13 (76.5)8 (100)0.134
Time from onset of symptoms to presentation (days)4 (2.0, 7.7)6 (3, 10)0.23
Severity of DKA, n (%)
 Severe20 (58.8)20 (62.5)0.95
 Moderate11 (32.4)11 (34.4)0.62
 Mild3 (8.8)1 (3.1)0.13
GCS at admission14 (11, 15)13 (10, 15)0.547
Hypotension at admission, n (%)2 (5.9)2 (6.3)0.95
Need for PICU, n (%)21 (61.8)14 (43.8)0.143
  1. *Kuppusamy Scale 2017, Data expressed as median (IQR)