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Table 3 Comparison of outcomes of patients with high or low (cortisoltotal/CRP) ratio

From: Cortisol total/CRP ratio for the prediction of hospital-acquired pneumonia and initiation of corticosteroid therapy in traumatic brain-injured patients

 Entire populationPlacebo Hydrocortisone treatment 
 Low (cortisoltotal/ CRP) ratioHigh (cortisoltotal/CRP) ratioP valuesLow (cortisoltotal/CRP) ratioHigh (cortisoltotal/CRP) ratioP valuesLow (cortisoltotal/CRP) ratioHigh (cortisoltotal/CRP) ratioP values
Hospital-acquired pneumonia39 (39.39)50 (62.50)0.00218 (37.50)32 (65.31)0.00621 (41.18)18 (58.06)0.138
 Pa02/Fi02 ratio146.5 [98–217]175.5 [133–232]0.147164.5 [130–217]175.5 [133.5–246]0.581122 [78–232.5]174 [132–227]0.156
 Septic shock5 (12.82)2 (4.00)0.2332 (11.11)00.1253 (14.29)2 (11.11)1.00
Other infections
 Meningitis2 (2.02)1 (1.25)1.0001 (2.08)00.4951 (1.96)1 (3.23)1.000
 Urinary tract infection9 (9.09)11 (13.75)0.3253 (6.25)10 (20.41)0.0416 (11.76)1 (3.23)0.245
 Bacteremia8 (8.08)5 (6.25)0.6394 (8.33)3 (6.12)0.7154 (7.84)2 (6.45)1.000
Organ failures
 Duration of vasopressor support, days4 [3–6]4 [2–6]0.9254 [3–6]5 (2–6]0.8374 [3–5.5]4 [2–6]0.787
 Acute respiratory distress syndrome18 (18.18)16 (20.00)0.7585 (10.42)9 (18.37)0.26513 (25.49)7 (22.58)0.766
 Acute kidney injury01 (1.25)0.4470001 (3.23)0.378
 SOFA day 19 [8–10]9 [7–10]0.5929 [8–9.5]9 [7–10]0.8779 [7–10]9 [7–10]0.511
 SOFA day 38 [6–9]8 [5.5–9]0.7068 [6–9]7 [5–9]0.3838 [6–9]8 [6–10]0.658
 SOFA day 74 [2–7]5 [4–6]0.3984 [2.5–6.5]4 [4–6]0.3525 [1–8]5 [4–6]0.810
Outcomes
 Antibiotic-free days at day 2821 [16–26]18.5 [11–21]0.00721.5 [15.5–26.5]19 [12–21]0.22521 [17–25]18 [11–22]0.52
 Mean duration of mechanic ventilation (days)11 [7–20]13 [8–19.5]0.72511.5 [7.5–18]12 [8–22]0.52511 [7–25]13 [9–19]0.86
 Mean duration of intensive care (days)15 [10–24]17 [11–28]0.28816 [11–22]17 [12–28]0.16715 [9–29]17 [10–28]0.867
Death in ICU
 In-ICU death8 (8.01)9 (11.25)0.4722 (4.17)5 (10.20)0.4366 (11.76)4 (12.90)1.000