Table 1 Baseline characteristics
Hospital-acquired pneumonia, no | Hospital-acquired pneumonia, yes | P value | |
|---|---|---|---|
N = 90 | N = 89 | ||
Age, years | 34 [23–48] | 31 [23–48] | 0.83 |
Men | 72 (80) | 74 (83.2) | 0.58 |
Medical history, No. (%) | |||
Renal insufficiency | 0 (0.00) | 1 (1.12) | 0.49 |
Cardiac insufficiency | 1 (1.11) | 1 (1.12) | 1.00 |
Chronic pulmonary disease | 1 (1.11) | 2 (2.25) | 0.62 |
Pathological admission status, median | |||
SAPS II | 42 [34–50] | 42 [37–50] | 0.29 |
Injury Severity Score | 18 [9–29] | 24 [13–30] | 0.10 |
Glasgow coma scale | 6 [4–7] | 6 [4–7] | 0.85 |
Associated Thoracic trauma (AIS ≥ 3) | 24 (26.67) | 29 (32.58) | 0.38 |
Events prior to admission, No. (%) | |||
Hemorrhagic shock | 5 (5.56) | 5 (5.62) | 0.98 |
Hypotension (systolic arterial pressure < 120 mmHg) | 24 (26.67) | 24 (26.97) | 0.96 |
Neurosurgery | 29 (32.22) | 22 (24.72) | 0.26 |
Etomidate use | 62 (68.89) | 64 (71.91) | 0.65 |
Blood transfusion | |||
Red cell units | 29 (32.22) | 21 (23.60) | 0.19 |
Frozen plasma units | 29 (32.22) | 23 (25.84) | 0.34 |
Systemic inflammatory response syndrome upon admission | |||
Cardiac rate > 120/min | 16 (17.78) | 13 (14.61) | 0.56 |
PaCO2, mmHg | 38 [33–41] | 37 [33–43] | 0.86 |
Body temperature > 39.0 °C | 18 (20) | 5 (5.6) | 0.004 |
Leucocytes count (g/L) | 11.9 [7.8–15.9] | 13.4 [10.3–16.5] | 0.06 |
Neutrophil count (g/L) | 8.4 [6–15.5] | 10.6 [8–14.5] | 0.19 |
Lymphocyt count (g/L) | 1.3 [0.8–2.2] | 1.2 [0.8–1.8] | 0.58 |
C-reactive protein (mg/mL) | 61 [35–98] | 53 [33–82] | 0.20 |
Short corticotropin test results | |||
Baseline blood cortisoltotal concentration, μg/L | 143 [92–201] | 168 [111–225] | 0.06 |
Baseline blood cortisolfree concentration, μg/L | 16.6 [6.6–39] | 21.9 [9.6–41] | 0.26 |
Transcortin blood level, μg/mL | 21.9 [14.9–47.3] | 27 [16.5–51.4] | 0.12 |
Delta total cortisolemia after 60 min after corticotropin, μg/L | 98 [30–161] | 84 [33–147] | 0.89 |
Ratio inflammatory response/cortisol response | |||
Cortisolfree/CRP | 0.25 [0.08–0.71] | 0.394 [0.17–0.80] | 0.10 |
Cortisoltotal/CRP | 2.30 [1.25–3.91] | 3.36 [1.74–5.09] | 0.021 |
Total Delta 60 min cortisol/CRP | 1.45 [0.51–2.73] | 1.55 [0.59–3.30] | 0.65 |