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Table 1 Baseline characteristics

From: Cortisol total/CRP ratio for the prediction of hospital-acquired pneumonia and initiation of corticosteroid therapy in traumatic brain-injured patients

 Hospital-acquired pneumonia, noHospital-acquired pneumonia, yesP value
 N = 90N = 89 
Age, years34 [23–48]31 [23–48]0.83
Men72 (80)74 (83.2)0.58
Medical history, No. (%)
 Renal insufficiency0 (0.00)1 (1.12)0.49
 Cardiac insufficiency1 (1.11)1 (1.12)1.00
 Chronic pulmonary disease1 (1.11)2 (2.25)0.62
Pathological admission status, median
 SAPS II42 [34–50]42 [37–50]0.29
 Injury Severity Score18 [9–29]24 [13–30]0.10
 Glasgow coma scale6 [4–7]6 [4–7]0.85
 Associated Thoracic trauma (AIS ≥ 3)24 (26.67)29 (32.58)0.38
Events prior to admission, No. (%)
 Hemorrhagic shock5 (5.56)5 (5.62)0.98
 Hypotension (systolic arterial pressure < 120 mmHg)24 (26.67)24 (26.97)0.96
 Neurosurgery29 (32.22)22 (24.72)0.26
 Etomidate use62 (68.89)64 (71.91)0.65
Blood transfusion
 Red cell units29 (32.22)21 (23.60)0.19
 Frozen plasma units29 (32.22)23 (25.84)0.34
Systemic inflammatory response syndrome upon admission
 Cardiac rate > 120/min16 (17.78)13 (14.61)0.56
 PaCO2, mmHg38 [33–41]37 [33–43]0.86
 Body temperature > 39.0 °C18 (20)5 (5.6)0.004
 Leucocytes count (g/L)11.9 [7.8–15.9]13.4 [10.3–16.5]0.06
  Neutrophil count (g/L)8.4 [6–15.5]10.6 [8–14.5]0.19
  Lymphocyt count (g/L)1.3 [0.8–2.2]1.2 [0.8–1.8]0.58
C-reactive protein (mg/mL)61 [35–98]53 [33–82]0.20
Short corticotropin test results
 Baseline blood cortisoltotal concentration, μg/L143 [92–201]168 [111–225]0.06
 Baseline blood cortisolfree concentration, μg/L16.6 [6.6–39]21.9 [9.6–41]0.26
 Transcortin blood level, μg/mL21.9 [14.9–47.3]27 [16.5–51.4]0.12
 Delta total cortisolemia after 60 min after corticotropin, μg/L98 [30–161]84 [33–147]0.89
Ratio inflammatory response/cortisol response
 Cortisolfree/CRP0.25 [0.08–0.71]0.394 [0.17–0.80]0.10
 Cortisoltotal/CRP2.30 [1.25–3.91]3.36 [1.74–5.09]0.021
 Total Delta 60 min cortisol/CRP1.45 [0.51–2.73]1.55 [0.59–3.30]0.65
  1. CRP C reactive protein. Results expressed as median (1st-3rd quartile) or N (%), SAPS II Simplified Acute Physiological Score, AIS Abbreviated Injury Scale