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Table 3 Factors associated with good neurological prognosis at ICU discharge in uni- and multivariate analysis in multiple imputation cohort (N = 3623 patients)

From: Temporal trends in the use of targeted temperature management after cardiac arrest and association with outcome: insights from the Paris Sudden Death Expertise Centre

CharacteristicsUnivariate analysisMultivariate analysis
Coefficient [95%CI]P valueCoefficient [95%CI]P value
Male1.65 [1.39–1.97]< 0.001
Age0.97 [0.96–0.98]< 0.0010.96 [0.95–0.97]< 0.001
Home location0.32 [0.27–0.38]< 0.0010.59 [0.47–0.74]< 0.001
Bystander CPR2.62 [2.16–3.19]< 0.0011.65 [1.19–2.28]0.003
Shockable rhythm9.70 [8.04–11.70]< 0.0012.96 [2.29–3.93]< 0.001
No flow > 3 min*0.38 [0.32–0.45]< 0.0010.48 [0.36–0.64]< 0.001
Low flow > 20 min*0.21 [0.17–0.26]< 0.0010.50 [0.38–0.66]< 0.001
Epinephrine use*0.06 [0.05–0.08]< 0.0010.15 [0.11–0.19]< 0.001
First arterial pH (by 0.1 unit)1.86 [1.73–2.00]< 0.0011.31 [1.20–1.45]< 0.001
Post-resuscitation shock0.44 [0.37–0.42]< 0.0010.73 [0.57–0.94]0.012
Early invasive coronary strategy8.16 [6.50–10.25]< 0.0013.24 [2.37–4.43]< 0.001
Targeted temperature management2.71 [2.30–3.19]< 0.0011.57 [1.22–2.02]< 0.001
Year of occurrence (2011 as reference)1.01 [0.96–1.05]0.75
  1. CPR cardiopulmonary resuscitation
  2. *Characteristics were dichotomized according to the median value