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Table 2 Multivariate analysis of risk factors for the development of new acute kidney injury

From: Cumulative fluid accumulation is associated with the development of acute kidney injury and non-recovery of renal function: a retrospective analysis

VariablesOR95% CI for ORp value
LowerUpper
Age1.001.001.010.24
BMI1.061.041.07<0.001
SOFA score on admission to the ICU1.041.001.080.05
Lowest MAP1.000.991.010.84
Sepsis1.110.801.530.53
Chronic kidney disease1.811.342.45<0.001
Atherosclerotic cardiovascular disease1.130.901.400.29
Congestive heart failure1.120.811.560.50
Diabetes mellitus1.060.851.330.60
Cancer0.840.691.030.10
Mechanical ventilation0.940.771.170.60
Norepinephrine use1.200.941.540.15
NSAID use0.480.221.050.07
Cumulative fluid balance on the day of AKI or day 3 in the ICU1.111.081.14<0.001
  1. Model diagnostics:
  2. There was no evidence of lack of fit (Hosmer Lemeshow p = 0.209) that the model was incorrectly specified (link test p = 0.300) or of multicollinearity among the included covariates (all variance inflation factors (VIF) < 1.5). There was no evidence of a non-linear relationship between cumulative fluid balance and AKI
  3. BMI body mass index, CI confidence interval, MAP mean arterial pressure, NSAID non-steroidal anti-inflammatory drug, SOFA Sequential Organ Failure Assessment, OR odd ratio