Table 1 Details of study characteristics of included studies
Study | Study design | Study setting | No. of patients | Mortality % | Peak PCT level | PCT level predicting outcomes | ||
|---|---|---|---|---|---|---|---|---|
Sepsis | MODS | Death | ||||||
Ren et al. [33] (China, 2016) | Prospective case-control | Trauma surgical department | 56 | – | Days 1 and 2 | Yes | – | – |
Wojtaszek et al. [34] (Poland, 2014) | Prospective cohort | – | 45 | Data not shown | Day 1 | No | – | Yes |
Rajkumari et al. [35] (India, 2013) | Prospective case-control | SICU | 275 | 10 | – | Yes | No | – |
Sakran et al. [36] (USA, 2012) | Prospective cohort | Trauma ICU | 102 | 13 | Days 1 and 2 | Yes | – | Yes |
Haasper et al. [37] (Germany, 2010) | Prospective cohort | ICU | 94 | 12 | Days 2 and 3 | No | Yes | – |
Keel et al. [38] (Switzerland, 2009) | Prospective cohort | Trauma center | 83 | 12 | Day 1 | Yes | – | – |
Castelli et al. [39] (Italy, 2009) | Prospective cohort | ICU | 94 | 5 | Day 1 | Yes | Yes | – |
Billeter et al. [40] (Switzerland, 2009) | Retrospective cohort | SICU | 1032 | 10 | Day 1 | Yes | – | – |
Maier et al. [41] (Germany, 2009) | Prospective cohort | – | 74 | – | Day 1 | – | – | – |
Balci et al. [42] (Turkey, 2009) | Prospective cohort | SICU | 113 | 44 | Days 1 and 7 | Yes | – | Yes |
Castelli et al. [43] (Italy, 2006) | Prospective cohort | ICU | 49 | – | Day 1 | Yes | Yes | – |
Ertugrul et al. [44] (Turkey, 2006) | Prospective case-control | SICU | 41 | – | – | No | – | – |
Meisner et al. [45] (Germany, 2006) | Prospective cohort | ICU | 90 | 17 | Day 1 | Yes | No | Yes |
Egger et al. [46] (Austria, 2004) | Prospective cohort | ICU | 26 | – | – | Yes | – | – |
Hensler et al. [47] (Germany, 2003) | Prospective case-control | Trauma center | 137 | 11 | Days 1 + 2 combined | No | Yes | No |
Andermahr et al. [48] (Germany, 2002) | Prospective case-control | ICU | 133 | 21 | Day 1 | No | – | – |
Oberholzer et al. [49] (Switzerland, 2000) | Prospective case-control | Trauma center | 1276 | 7 | Day 1 | Yes | Yes | – |
Wanner et al. [50] (Germany, 2000) | Retrospective case-control | ICU | 405 | 23 | Days 1 and 3 | Yes | Yes | No |
Mimoz et al. [51] (France, 1998) | Prospective cohort | SICU | 21 | 14 | Day 1 | No | Yes | – |