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Table 4 Prognostic performance for 28-day mortality of the 25% SOFA decrease cutoff on day 7 ΔSOFA using post-hoc derivation and validation cohorts

From: The early change of SOFA score as a prognostic marker of 28-day sepsis mortality: analysis through a derivation and a validation cohort

 

Cohort A

Total

Cohort B

Total

Non-survivors (n)

Survivors (n)

Non-survivors (n)

Survivors (n)

≥ 25% SOFA decrease

74

Sens: 86.0%

PPV: 51.7%

69

143

61

Sens: 91.3%

PPV: 41.5%

86

147

< 25% SOFA decrease

12

169

Spec:71.0%

NPV: 93.4%

181

14

162

Spec: 65.3%

NPV: 92.0%

176

 

86

238

324

75

248

323

  1. Abbreviations: NPV negative predictive value, PPV positive predictive value, Sens sensitivity, Spec specificity