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Table 4 Prognostic performance for 28-day mortality of the 25% SOFA decrease cutoff on day 7 ΔSOFA using post-hoc derivation and validation cohorts

From: The early change of SOFA score as a prognostic marker of 28-day sepsis mortality: analysis through a derivation and a validation cohort

 Cohort ATotalCohort BTotal
Non-survivors (n)Survivors (n)Non-survivors (n)Survivors (n)
≥ 25% SOFA decrease74
Sens: 86.0%
PPV: 51.7%
6914361
Sens: 91.3%
PPV: 41.5%
86147
< 25% SOFA decrease12169
Spec:71.0%
NPV: 93.4%
18114162
Spec: 65.3%
NPV: 92.0%
176
 8623832475248323
  1. Abbreviations: NPV negative predictive value, PPV positive predictive value, Sens sensitivity, Spec specificity