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Table 3 Comparative prognostic performance for 90-day mortality of the less than 25% SOFA decrease cutoff on day 7 ΔSOFA between the derivation and validation cohorts

From: The early change of SOFA score as a prognostic marker of 28-day sepsis mortality: analysis through a derivation and a validation cohort

 

Derivation cohort (95% CI)

Validation cohort (95% CI)

p value

Sensitivity

74.6% (69.5–83.4)

77.1% (69.5–83.4)

0.63

Specificity

81.8% (77.1–85.7)

47.8% (33.1–62.9)

2.00 × 10−5

PPV

59.5% (51.1–67.4)

83.1% (75.7–88.7)

9.00 × 10−5

NPV

90.0% (85.9–93.1)

38.6% (26.3–52.4)

1.54 × 10−27

  1. Abbreviations: CI confidence interval, NPV negative predictive value, PPV positive predictive value
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Critical Care

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