All (n = 18) | HIV (n = 6) | non-HIV (n = 12) | p value | |
---|---|---|---|---|
Age (years) | 49.7 ± 18.4 | 36.8 ± 9.7 | 56.2 ± 18.6 | 0.032 |
Sex (male) | 11 (61.1%) | 4 (66.7%) | 7 (58.3%) | 1.0 |
BMI (kg/m2) | 24.6 ± 3.4 | 23.0 ± 4.2 | 25.5 0 ± 2.6 | 0.149 |
Underlying pulmonary disease* | 2 (11.1%) | 0 (0%) | 2 (16.7%) | 0.407 |
Comorbidities | ||||
Hypertension | 5 (27.8%) | 0 (0%) | 5 (41.27%) | 0.114 |
Renal insufficiency | 2 (11.1%) | 0 (0%) | 2 (16.7%) | 0.529 |
Chronic haemodialysis | 1 (5.6%) | 0 (0%) | 1 (8.3%) | 1.0 |
MV pre-ECMO | ||||
PEEP (mbar) | 14.9 ± 3.1 | 13.8 ± 2.9 | 15.3 ± 3.2 | 0.489 |
Plateau pressure (mbar) | 28.5 ± 4.6 | 29.3 ± 4.0 | 28.2 ± 4.9 | 0.571 |
Driving pressure (mbar) | 13.6 ± 4.2 | 15.5 ± 4.5 | 12.9 ± 4.1 | 0.412 |
Tidal volume (ml) | 390.7 ± 107.9 | 362.5 ± 104.4 | 400.9 ± 112.3 | 0.571 |
Minute volume (l/min) | 9.9 ± 3.6 | 10.6 ± 4.3 | 9.6 ± 3.5 | 0.571 |
Compliance (ml/mbar) | 32.7 ± 15.8 | 23.3 ± 10.4 | 35.5 ± 17.0 | 0.226 |
FiO2 (%) | 83.8 ± 19.4 | 87.5 ± 19.4 | 81.8 ± 19.4 | 0.660 |
Horowitz index (mmHg) | 87.6 ± 37.6 | 90.8 ± 40.8 | 85.8 ± 37.6 | 1.0 |
D(A-a)O2 (mmHg) | 466.4 ± 133.4 | 481.7 ± 132.9 | 458.1 ± 139.4 | 0.884 |
MV duration before ECMO (days) | 5.4 ± 5.4 | 9.3 ± 6.5 | 3.3 ± 3.3 | 0.048 |
Acute renal failure | 3 (16.7%) | 0 (0%) | 3 (25.0%) | 0.276 |
LDHmax (U/l) before ECMO | 734.1 ± 268.2 | 577.2 ± 182.1 | 812.5 ± 275.5 | 0.083 |
Scores | ||||
SOFA score | 9.7 ± 3.6 | 8.7 ± 3.4 | 10.3 ± 3.7 | 0.733 |
APACHE II score | 24.9 ± 8.1 | 25.0 ± 9.0 | 24.9 ± 8.1 | 0.961 |
RESP score | − 3.3 ± 3.2 | − 2.8 ± 1.9 | − 3.55 ± 3.8 | 1.0 |
Successful ECMO weaning | 7 (38.9%) | 3 (50%) | 4 (33.3%) | 0.494 |
Survival† | 4 (22.2%) | 3 (50%) | 1 (8.3%) | 0.045 |
ICU length of stay (days) | 26.2 ± 20.5 | 33.8 ± 15.4 | 22.4 ± 22.3 | 0.053 |
ECMO duration (days) | 13.2 ± 8.7 | 13.8 ± 11.0 | 12.9 ± 7.8 | 0.892 |
MV duration (days) | 20.8 ± 14.8 | 25.2 ± 17.1 | 18.4 ± 13.7 | 0.462 |
Acute haemodialysis | 6 (33.3%) | 0 (0%) | 6 (50.0%) | 0.054 |
Prone position while ECMO | 11 (61.1%) | 5 (83.3%) | 6 (50.0%) | 0.588 |