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Table 1 Comparison of key clinical characteristics across phenotypes (N = 118)

From: Murine sepsis phenotypes and differential treatment effects in a randomized trial of prompt antibiotics and fluids

Characteristic

All mice

Class 1

Class 2

p valueb

No.

118

21

97

 

Time to deterioration [h]: mean (SD)

7.7 (1.8)

9.7 (3.2)

7.3 (0.9)

< 0.001

Heart rate 5 h after CLP [bpm]: mean (SD)

590 (79)

592 (108)

589 (71)

0.87

Temperature 5 h after CLP [°C]: mean (SD)

32.3 (1.7)

32.7 (1.4)

32.2 (1.7)

0.17

Heart rate 7 h after CLP [bpm]: mean (SD)

580 (58)

626 (35)

564 (55)

< 0.001

Temperature 7 h after CLP [°C]: mean (SD)

32.1 (1.7)

33.5 (1.3)

31.6 (1.6)

< 0.001

Time to deatha [h]: mean (SD)

52.5 (26.3)

51.6 (20.3)

52.7 (27.6)

0.88

  1. Abbreviations: No. number, h hours, SD standard deviation, CLP cecal ligation and puncture, bpm beats per minute
  2. aTime to death available in 17 mice in class 1 and 73 mice in class 2
  3. bp value compares class 1 to class 2 using ANOVA
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