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Table 2 Main clinical outcomes according to the presence of severe intensive care unit-acquired diaphragm dysfunction (S-ICU-DD) and intensive care unit-acquired weakness (ICU-AW)

From: Respective contribution of intensive care unit-acquired limb muscle and severe diaphragm weakness on weaning outcome and mortality: a post hoc analysis of two cohorts

  No S-ICU-DD S-ICU-DD p
No weakness ICU-AW No weakness ICU-AW
N 36 (31%) 32 (28%) 14 (12%) 34 (29%)  
Outcomes
 SBT failure, n (%) 7 (19) 14 (44)* 7 (58)* 26 (72)*# < 0.0001
 Reintubation after extubation following successful SBT, n (%) 3 (8) 6 (19)* 1 (8) 8 (23)* 0.039
 Weaning failure, n (%) 10 (28) 20 (63)* 8 (67)* 31 (86)*# < 0.0001
 MV until extubation, days 4 (1–6) 7 (4–13)* 7 (3–8) 13 (7–24)* < 0.0001
 ICU length of stay, days 5 (3–14) 15 (7–30)* 9 (4–13)# 20 (9–30)* < 0.0001
 ICU mortality, n (%) 3 (8) 4 (13) 0 (0) 14 (39)*#† 0.001
  1. Data are expressed as median (interquartile range) or n (%)
  2. SBT spontaneous breathing trial, MV mechanical ventilation, ICU intensive care unit
  3. *vs. No S-ICU-DD–No ICU-AW
  4. #vs. No S-ICU-DD–ICU-AW
  5. vs. S-ICU-DD–No ICU-AW