Table 1 Demographic and baseline characteristics of ICU patients with Stenotrophomonas maltophilia hospital-acquired pneumonia
Variables | Total N = 282 |
|---|---|
Gender, male | 197 (69.9) |
Age, years | 65 [56–74] |
BMI (kg m− 2) | 25.3 [22–28.8] |
Reason for ICU admission | |
Medical condition | 167 (59.2) |
Scheduled surgery | 32 (11.3) |
Emergent surgery | 83 (29.4) |
Postoperative period of cardiac surgery | 60 (21.3) |
Previous carriage of S. maltophilia | 13 (4.6) |
Pulmonary comorbidities | |
Chronic obstructive pulmonary disease | 51 (18.1) |
Chronic respiratory insufficiency | 30 (10.6) |
Cystic fibrosis | 2 (0.7) |
Other comorbidities | |
Hypertension | 147 (52.1) |
Congestive heart failure | 66 (23.4) |
Dialysis-dependent chronic kidney disease | 8 (2.8) |
Liver cirrhosis | 22 (7.8) |
Insulin-requiring diabetes | 31 (11) |
Severe neurologic disability | 30 (10.6) |
Habits | |
Active smoking | 86 (30.5) |
Chronic alcohol abuse | 47 (16.7) |
Drug abuse | 8 (2.8) |
Immune comprise conditions (n, %) | |
Neutropenia | 1 (0.3) |
HIV and/or CD4 count < 50/mm3 | 1 (0.3) |
Recent or ongoing chemotherapy | 11 (3.9) |
Hematologic malignancy | 16 (5.7) |
Solid tumor being actively treated | 20 (7.1) |
Solid tumor in remission | 22 (7.8) |
Immunosuppressive therapy or corticosteroids use > 0.5 mg/kg > 30 days | 34 (12) |
Innate or acquired immune deficiency | 1 (0.3) |
Severity scores | |
SOFA score at admission | 8 [5–11] |
SAPS II at 24 h | 47 [36–63] |
Ventilator-associated pneumonia | 228 (80.8) |
Duration of ventilation before S. maltophilia HAP, days | 11 [5–18] |
ICU length of stay, days | 32 [19–58] |
Hospital length of stay, days | 54 [30–94] |
Number of days between hospital admission and S. maltophilia HAP | 16 [8–27] |
Number of days between ICU admission and S. maltophilia HAP | 11 [5–19] |
Mortality | 140 (49.7) |
Mortality directly attributable to S. maltophilia | 34 (24.3) |