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Table 1 Selected characteristics of the included studies

From: Value of respiratory variation of aortic peak velocity in predicting children receiving mechanical ventilation: a systematic review and meta-analysis

No. Authors/year Sample size Age (months) Settings or time point of measure VE Golden index (responders) Tool measuring golden index Tool measuring VPeak Tide volume (ml/kg) PEEP (cmH2O) Vasoactive drugs
1 Durand 2008 26 M = 28.5 ICU 20 ml /kg/6%HES or saline 15–30 min SV > 15% TTE TTE 7.4 4 Yes
2 Choi 2010 21 A = 30 VSD repair, 1 h after arriving at ICU 10 ml/ kg/6%HES over 20 min SV > 15% TTE TTE 10 0 Yes
3 Renner 2011 27 A = 17 Before cardiac surgery begin 10 ml/ kg/6%HES SVI > 15% TOE TOE 10 3–5 Yes
4 Pereira 2011 30 A = 112 Before neurosurgery incision 20 ml /kg/saline over 15 min VTI > 15% TTE TTE 10 0–2 Yes
5 Byon 2013 33 A = 72.1 Stable during neurosurgery 10 ml/ kg/6%HES 10 min SVI > 10% TTE TTE 10 0 UC
6 Lee 2014 26 A = 28 VSD repair, 30 min after arriving at ICU 10 ml/ kg/6%HES 20 min SV > 15% TTE TTE 10 5 Yes
7 Lee 2015 29 A = 13.7 Once sternum closed after VSD repair 10 ml/ kg/6%HES 10 min SVI > 15% TOE TOE 10 UC Yes
8 Krishna 2016 42 A = 76 General endotracheal anesthesia 10 ml/ kg/1%DRL 5-10 min SVI ≥ 15% TTE TTE 10 0 UC
9 Favia 2017 16 A = 24.2 Sternal closure in cardiac surgery 10 ml /kg/crystalloid or blood products CI > 10% MostCare™ TOE 8–10 0–10 No
10 Lee 2017 30 A = 19.2 After cardiac surgery end before entering ICU 10 ml/ kg/6%HES 20 min SVI > 15% TOE TOE 10 UC Yes
11 Morparia 2018 22 A==69.8 Neurosurgery 10 ml/ kg/crystalloid SV > 15% TTE TTE 8–10 0–4 sNO
  1. A average age, min minute, M median age, VE volume experiment, HES hydroxyethe1 starch, DRL dextrose Ringer’s lactate, VPeak respiratory variation of aortic peak velocity, VSD ventricular septal defect, PEEP positive end-expiratory pressure, UC unclear, SV stroke volume, SVI stroke volume index, VTI velocity-time integral, TTE transthoracic echocardiography, TOE transoesophageal echocardiography