Value of respiratory variation of aortic peak velocity in predicting children receiving mechanical ventilation: a systematic review and meta-analysis

Table 1 Selected characteristics of the included studies

No.	Authors/year	Sample size	Age (months)	Settings or time point of measure	VE	Golden index (responders)	Tool measuring golden index	Tool measuring △VPeak	Tide volume (ml/kg)	PEEP (cmH₂O)	Vasoactive drugs
1	Durand 2008	26	M = 28.5	ICU	20 ml /kg/6%HES or saline 15–30 min	△SV > 15%	TTE	TTE	7.4	4	Yes
2	Choi 2010	21	A = 30	VSD repair, 1 h after arriving at ICU	10 ml/ kg/6%HES over 20 min	△SV > 15%	TTE	TTE	10	0	Yes
3	Renner 2011	27	A = 17	Before cardiac surgery begin	10 ml/ kg/6%HES	△SVI > 15%	TOE	TOE	10	3–5	Yes
4	Pereira 2011	30	A = 112	Before neurosurgery incision	20 ml /kg/saline over 15 min	△VTI > 15%	TTE	TTE	10	0–2	Yes
5	Byon 2013	33	A = 72.1	Stable during neurosurgery	10 ml/ kg/6%HES 10 min	△SVI > 10%	TTE	TTE	10	0	UC
6	Lee 2014	26	A = 28	VSD repair, 30 min after arriving at ICU	10 ml/ kg/6%HES 20 min	△SV > 15%	TTE	TTE	10	5	Yes
7	Lee 2015	29	A = 13.7	Once sternum closed after VSD repair	10 ml/ kg/6%HES 10 min	△SVI > 15%	TOE	TOE	10	UC	Yes
8	Krishna 2016	42	A = 76	General endotracheal anesthesia	10 ml/ kg/1%DRL 5-10 min	△SVI ≥ 15%	TTE	TTE	10	0	UC
9	Favia 2017	16	A = 24.2	Sternal closure in cardiac surgery	10 ml /kg/crystalloid or blood products	△CI > 10%	MostCare™	TOE	8–10	0–10	No
10	Lee 2017	30	A = 19.2	After cardiac surgery end before entering ICU	10 ml/ kg/6%HES 20 min	△SVI > 15%	TOE	TOE	10	UC	Yes
11	Morparia 2018	22	A==69.8	Neurosurgery	10 ml/ kg/crystalloid	△SV > 15%	TTE	TTE	8–10	0–4	sNO

A average age, min minute, M median age, VE volume experiment, HES hydroxyethe1 starch, DRL dextrose Ringer’s lactate, △VPeak respiratory variation of aortic peak velocity, VSD ventricular septal defect, PEEP positive end-expiratory pressure, UC unclear, SV stroke volume, SVI stroke volume index, VTI velocity-time integral, TTE transthoracic echocardiography, TOE transoesophageal echocardiography

ISSN: 1364-8535