Time to antibiotic use (min) | p value | ||||||
---|---|---|---|---|---|---|---|
0–60 | 61–120 | 121–180 | 181–240 | 241–360 | 361–1440 | ||
Crude in-hospital mortality among all patients, n/total (%), n = 1124 | 96/343 (28.0) | 66/327 (20.2) | 35/161 (21.7) | 19/94 (20.2) | 26/103 (25.2) | 21/96 (21.9) | 0.219 |
Crude in-hospital mortality among patients with septic shock, n/total (%), n = 703 | 68/215 (31.6) | 47/207 (22.7) | 27/94 (28.7) | 16/61 (26.2) | 21/69 (30.4) | 16/57 (28.1) | 0.466 |
Crude in-hospital mortality among patients from ED, n/total (%), n = 631 | 61/210 (29.1) | 36/194 (18.6) | 14/94 (14.9) | 8/45 (17.8) | 15/56 (26.8) | 4/32 (12.5) | 0.022 |
Adjusted in-hospital mortality among all patients (95% CI)a, n = 949 | 28.7 (23.3–34.1)* | 21.6 (16.5–26.6)* | 23.2 (16.4–30.0) | 20.4 (12.1–28.7) | 20.5 (12.6–28.5) | 21.1 (12.5–29.7) | |
Adjusted in-hospital mortality among patients with septic shock (95% CI)a, n = 615 | 30.0 (23.5–36.5) | 22.3 (16.1–28.5) | 28.5 (19.3–37.6) | 27.4 (15.9–38.9) | 25.1 (15.2–35.1) | 21.6 (11.1–32.0) | |
Adjusted in-hospital mortality among patients from ED (95% CI)a, n = 503 | 27.9 (21.1–34.6)* | 18.4 (12.2–24.5)* | 17.8 (9.3–26.2) | 17.2 (5.4–28.9) | 24.1 (12.2–36.0) | 12.8 (5.7–25.0) | |
Crude 28-day mortality, n/total (%), n = 1112 | 75/338 (22.2) | 55/325 (16.9) | 26/159 (16.4) | 15/92 (16.3) | 22/103 (21.4) | 17/95 (17.9) | 0.445 |
ICU-free days, median (IQR), n = 902 | 20 (12–24) | 20 (13–24) | 20 (9–23) | 18 (6–24) | 18 (10–24) | 19 (1023) | 0.3522 |
Ventilator-free days | 21 (0–28) | 21 (8–28) | 22 (0–28) | 20 (0–27) | 21 (0–27) | 20 (0–28) | 0.3947 |
Length of hospital stay | 26 (13–46) | 22 (11–43) | 26 (13–49) | 21 (13–38) | 25 (12–54) | 29 (13–48) | 0.4827 |