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Table 2 Classical respiratory mechanics parameters

From: Effects of inspiratory flow on lung stress, pendelluft, and ventilation heterogeneity in ARDS: a physiological study

 

PEEP 5 cmH2O

PEEP 15 cmH2O

p value

Inspiratory flow

Inspiratory flow

Flow

PEEP

Interaction

Low

Medium

High

Low

Medium

High

  

Ppeak, cmH2O

21*,† [19–24]

28 [23–33]

39 [34–45]

31*,† [28–33]

36 [35–41]

47 [44–51]

<0.001

<0.001

<0.001

P1, cmH2O

17 [15–20]

17 [16–19]

18 [17–20]

27 [25–29]

28 [26–29]

28 [26–31]

0.007

<0.001

0.889

Pplat, cmH2O

15 [15–18]

15 [14–16]

15 [14–16]

26 [24–26]

25 [23–26]

26 [24–27]

0.262

<0.001

0.568

PEEPtot, cmH2O

6 [5–7]

6 [5–6]

5 [5–6]

16*,† [15,16]

15 [15–15]

15 [15–15]

0.003

<0.001

0.442

Driving P, cmH2O

10 [8–11]

9 [8–11]

10 [8–11]

10 [9–11]

10 [8–11]

10 [9–12]

0.017

0.539

0.455

  1. Ppeak peak airway pressure, P1 end-inspiratory airway pressure at 0 flow, Pplat end-inspiratory plateau airway pressure, PEEPtot total (set + intrinsic) positive end-expiratory pressure, Driving P driving airway pressure
  2. *p < 0.05 vs medium inspiratory flow; †p < 0.05 vs high inspiratory flow