Analyses | Metrics of score performance | Bootstrap comparisons | |||||
---|---|---|---|---|---|---|---|
TRIAGES score | RTS | MGAP score | TRIAGES score versus RTS | TRIAGES score versus MGAP score | |||
Difference [95%CI] | P | Difference [95%CI] | P | ||||
Primary analysis | |||||||
Area under curve | |||||||
JTDB validation cohort (n = 76,762) | 0.932 | 0.907 | 0.918 | 0.025 [0.023, 0.028] | < 0.001 | 0.014 [0.012, 0.016] | < 0.001 |
CRASH-2 cohort (n = 19,740) | 0.814 | 0.808 | 0.774 | 0.006 [0.001, 0.011] | 0.010 | 0.040 [0.033, 0.047] | < 0.001 |
Sensitivity analyses for the primary analysis | |||||||
Area under curve | |||||||
Multiple imputation | |||||||
JTDB validation cohort (n = 110,884) | 0.917 | 0.894 | 0.902 | 0.023 [0.020, 0.025] | < 0.001 | 0.015 [0.013, 0.017] | < 0.001 |
CRASH-2 cohort (n = 20,197) | 0.816 | 0.810 | 0.776 | 0.006 [0.002, 0.011] | 0.006 | 0.040 [0.034, 0.046] | < 0.001 |
Single imputation by the best value | |||||||
JTDB validation cohort (n = 97,248) | 0.911 | 0.889 | 0.899 | 0.022 [0.019, 0.024] | < 0.001 | 0.012 [0.009, 0.014] | < 0.001 |
CRASH-2 cohort (n = 20,197) | 0.813 | 0.806 | 0.776 | 0.006 [0.002, 0.011] | 0.006 | 0.037 [0.031, 0.043] | < 0.001 |
Prehospital variables | |||||||
JTDB validation cohort (n = 110,885) | 0.858 | 0.786 | 0.833 | 0.072 [0.066, 0.078] | < 0.001 | 0.025 [0.021, 0.030] | < 0.001 |
Secondary analyses | |||||||
Partial area under curve (sensitivity ≥ 0.9) | |||||||
JTDB validation cohort (n = 110,885) | 0.764 | 0.652 | 0.722 | 0.112 [0.102, 0.121] | < 0.001 | 0.042 [0.033, 0.050] | < 0.001 |
CRASH-2 cohort (n = 20,197) | 0.629 | 0.592 | 0.560 | 0.037 [0.026, 0.048] | < 0.001 | 0.069 [0.057, 0.081] | < 0.001 |
Net reclassification improvement | |||||||
JTDB validation cohort (n = 110,885) | 0.465 [0.441, 0.489] | < 0.001 | 0.422 [0.396, 0.447] | < 0.001 | |||
CRASH-2 cohort (n = 20,197) | 0.230 [0.177, 0.312] | 0.004 | 0.239 [0.176, 0.318] | < 0.001 |