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Table 1 Baseline characteristics of non-ARDS and ARDS participants

From: Association between hospital mortality and inspiratory airway pressures in mechanically ventilated patients without acute respiratory distress syndrome: a prospective cohort study

 

Non-ARDS (n = 822)

ARDS (n = 310)

p value

Age (years)

60.3 (16.6)

59.1 (15.9)

0.23

Male

440 (53.5)

170 (54.8)

0.69

African-American

209 (25.4)

61 (19.7)

0.04

Medical ICU

375 (45.6)

164 (52.9)

< 0.001

Initial admitting diagnosisa

 Respiratory

416 (50.6)

230 (74.2)

< 0.001

 Neurological

251 (30.5)

48 (15.5)

< 0.001

 Cardiovascular

226 (27.5)

84 (27.1)

0.89

 Infectious

221 (26.9)

138 (44.5)

< 0.001

 Gastrointestinal

122 (14.8)

44 (14.2)

0.78

 Trauma

61 (7.4)

9 (2.9)

0.005

 Endocrine

38 (4.6)

12 (3.9)

0.58

 Other

134 (16.3)

37 (11.9)

0.067

Sepsis

261 (31.8)

190 (61.7)

< 0.001

Pneumonia

250 (30.4)

148 (47.7)

< 0.001

APACHE II

20.2 (7.4)

22.1 (7.7)

< 0.001

SOFA

6 (4–9)

8 (5–11)

< 0.001

PaO2/FiO2

255.6 (150.7)

174.8 (102.3)

< 0.001

Compliance respiratory system

39.6 (28.2)

35.1 (35.6)

0.04

Plateau pressure

20.6 (6.5)

23.9 (7.1)

< 0.001

Driving pressure

14.3 (6.0)

16.0 (6.4)

< 0.001

PEEP

5 (5–8)

7 (5–10)

< 0.001

Tidal volume (mL/kg PBW)

7.2 (1.21)

6.78 (1.19)

< 0.001

Hospital LOS

18 (10–30)

19 (10–33)

0.43

ICU LOS

10 (5–17)

11 (6–18)

0.04

Ventilator days

7 (3–14)

9 (5–15)

0.01

Mortality

224 (27.3)

120 (38.7)

< 0.001

  1. Abbreviations: ARDS acute respiratory distress syndrome, APACHE Acute Physiologic and Chronic Health Evaluation, SOFA Sequential Organ Failure Assessment, ICU intensive care unit, PEEP positive end-expiratory pressure, PBW predicted body weight, LOS length of stay
  2. Data presented as mean (SD), median (IQR), or n (%)
  3. aMay have more than one admitting diagnosis. Does not sum to 100%