Table 3 Patient demography and clinical characteristics of the critically ill patients (Pitt bacteremia score ≥ 4) surviving at or dying within 30 days after bacteremia onset*
Variables | Patient number (%) | P value** | ||
|---|---|---|---|---|
Total n = 646 | Death n = 302 | Survival n = 344 | ||
Patient demography | ||||
 Age, years, mean ± SD | 70.5 ± 15.8 | 70.6 ± 14.9 | 70.3 ± 16.5 | 0.79 |
 Gender, male | 370 (57.3) | 184 (60.9) | 186 (54.1) | 0.08 |
 Nursing-home residents | 82 (12.7) | 39 (12.9) | 43 (12.5) | 0.88 |
Time-to-appropriate antibiotic, h, median ± IQR | 2 (1–7) | 2 (1–15) | 2 (1–5) | < 0.001 |
Inadequate source control during antibiotic therapy | 26 (4.0) | 17 (5.6) | 9 (2.6) | 0.05 |
Major bacteremia sources | ||||
 Pneumonia | 228 (35.3) | 133 (44.0) | 95 (27.6) | < 0.001 |
 Urinary tract | 133 (20.6) | 26 (8.6) | 107 (31.1) | < 0.001 |
 Skin and soft-tissue | 61 (9.4) | 30 (9.9) | 31 (9.0) | 0.69 |
 Intra-abdominal | 59 (9.1) | 28 (9.3) | 31 (9.0 | 0.91 |
 Primary bacteremia | 45 (7.0) | 29 (9.6) | 16 (4.7) | 0.01 |
 Biliary tract | 37 (5.7) | 11 (3.6) | 26 (7.6) | 0.03 |
 Liver abscess | 22 (3.4) | 6 (2.0) | 16 (4.7) | 0.06 |
 Infective endocarditis | 18 (2.8) | 5 (1.7) | 13 (3.8) | 0.10 |
Fatal comorbidities (McCabe classification) | 211 (32.7) | 124 (41.1) | 87 (25.3) | < 0.001 |
Major comorbidities | ||||
 Hypertension | 308 (47.7) | 140 (46.4) | 168 (48.8) | 0.53 |
 Diabetes mellitus | 250 (38.7) | 107 (35.4) | 143 (41.6) | 0.11 |
 Neurological diseases | 235 (36.4) | 97 (32.1) | 138 (40.1) | 0.04 |
 Malignancies | 220 (34.1) | 125 (41.4) | 95 (27.6) | < 0.001 |
 Chronic kidney diseases | 114 (17.6) | 49 (16.2) | 65 (18.9) | 0.37 |
 Liver cirrhosis | 76 (11.8) | 46 (15.2) | 30 (8.7) | 0.01 |
 Coronary artery diseases | 64 (9.9) | 31 (10.3) | 33 (9.6) | 0.78 |