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Table 8 Predicted activation or deactivation of specific pathways based on MDSC mRNA expression from septic day 14 patients

From: Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis

Diseases or function

Predicted activation state Z-score

Inflammatory response*

2.187

Growth of malignant tumor*

2.607

Proliferation of cancer cells*

2.414

Proliferation of lymphatic system cells#

− 2.351

  1. The top pathways and their corresponding Z-score within the functional category in severe sepsis/septic shock patients 14 days after insult
  2. *The pathway is predicted to have significant activation
  3. #The pathway is predicted to be downregulated