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Fig. 4 | Critical Care

Fig. 4

From: Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis

Fig. 4

IL-2 concentration in functional T cell proliferation and suppression assay supernatants. After 4 days of cell culture in the following groups: (1) unstimulated T cells in culture medium, (2) CD3/28-stimulated T cells in culture medium, and (3) CD3/28-stimulated T cells in the presence of culture medium and MDSCs (1:1), supernatant was collected for quantification of IL-2 concentration (pg/ml) in septic patients from days 4 (n = 7) and 14 (n = 7). Concentration levels of IL-2 were significantly different (p = 0.03) between stimulated T cells at days 4 and 14 and between stimulated T cells and stimulated T cells + MDSCs at day 14 (p = 0.02)

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