TY - JOUR AU - Mares, C. A. AU - Sharma, J. AU - Ojeda, S. S. AU - Li, Q. AU - Campos, J. A. AU - Morris, E. G. PY - 2010 DA - 2010// TI - Attenuated response of aged mice to respiratory Francisella novicida is characterized by reduced cell death and absence of subsequent hypercytokinemia JO - PLoS One VL - 5 UR - https://doi.org/10.1371/journal.pone.0014088 DO - 10.1371/journal.pone.0014088 ID - Mares2010 ER - TY - JOUR AU - Singer, M. AU - Deutschman, C. S. AU - Seymour, C. W. AU - Shankar-Hari, M. AU - Annane, D. AU - Bauer, M. PY - 2016 DA - 2016// TI - The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) JO - JAMA. VL - 315 UR - https://doi.org/10.1001/jama.2016.0287 DO - 10.1001/jama.2016.0287 ID - Singer2016 ER - TY - JOUR AU - Plevin, R. AU - Callcut, R. PY - 2017 DA - 2017// TI - Update in sepsis guidelines: what is really new? JO - Trauma Surg Acute Care Open VL - 2 UR - https://doi.org/10.1136/tsaco-2017-000088 DO - 10.1136/tsaco-2017-000088 ID - Plevin2017 ER - TY - STD TI - National Inpatient Hospital Costs. The most expensive conditions by payer, 2013: Agency for Healthcare Research and Quality; 2016. Available from: https://www.hcup-us.ahrq.gov/reports/statbriefs/sb204-Most-Expensive-Hospital-Conditions.jsp. Accessed May 2019. UR - https://www.hcup-us.ahrq.gov/reports/statbriefs/sb204-Most-Expensive-Hospital-Conditions.jsp ID - ref4 ER - TY - STD TI - Seventieth World Health Assembly update, 26 May 2017 [press release]. World Health Organization, May 26, 2017 2017. ID - ref5 ER - TY - JOUR AU - Brakenridge, S. c. o. t. t. C. AU - Efron, P. h. i. l. i. p. A. AU - Cox, M. i. c. h. a. e. l. C. AU - Stortz, J. u. l. i. e. A. AU - Hawkins, R. u. s. s. e. l. l. B. AU - Ghita, G. a. b. r. i. e. l. a. AU - Gardner, A. n. n. a. AU - Mohr, A. l. i. c. i. a. M. AU - Anton, S. t. e. p. h. e. n. D. AU - Moldawer, L. y. l. e. L. AU - Moore, F. r. e. d. e. r. i. c. k. A. PY - 2019 DA - 2019// TI - Current Epidemiology of Surgical Sepsis JO - Annals of Surgery VL - 270 UR - https://doi.org/10.1097/SLA.0000000000003458 DO - 10.1097/SLA.0000000000003458 ID - Brakenridge2019 ER - TY - JOUR AU - Mira, J. C. AU - Gentile, L. F. AU - Mathias, B. J. AU - Efron, P. A. AU - Brakenridge, S. C. AU - Mohr, A. M. PY - 2017 DA - 2017// TI - Sepsis pathophysiology, chronic critical illness, and persistent inflammation-immunosuppression and catabolism syndrome JO - Crit Care Med VL - 45 UR - https://doi.org/10.1097/CCM.0000000000002074 DO - 10.1097/CCM.0000000000002074 ID - Mira2017 ER - TY - JOUR AU - Gentile, L. F. AU - Cuenca, A. G. AU - Efron, P. A. AU - Ang, D. AU - Bihorac, A. AU - McKinley, B. A. PY - 2012 DA - 2012// TI - Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care JO - J Trauma Acute Care Surg VL - 72 UR - https://doi.org/10.1097/TA.0b013e318256e000 DO - 10.1097/TA.0b013e318256e000 ID - Gentile2012 ER - TY - JOUR AU - Goodwin, A. J. AU - Rice, D. A. AU - Simpson, K. N. AU - Ford, D. W. PY - 2015 DA - 2015// TI - Frequency, cost, and risk factors of readmissions among severe sepsis survivors JO - Crit Care Med VL - 43 UR - https://doi.org/10.1097/CCM.0000000000000859 DO - 10.1097/CCM.0000000000000859 ID - Goodwin2015 ER - TY - JOUR AU - Yende, S. AU - Austin, S. AU - Rhodes, A. AU - Finfer, S. AU - Opal, S. AU - Thompson, T. PY - 2016 DA - 2016// TI - Long-term quality of life among survivors of severe sepsis: analyses of two international trials JO - Crit Care Med VL - 44 UR - https://doi.org/10.1097/CCM.0000000000001658 DO - 10.1097/CCM.0000000000001658 ID - Yende2016 ER - TY - STD TI - Stortz JA, Mira JC, Raymond SL, Loftus TJ, Ozrazgat Baslanti T, Wang Z, et al. Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients. J Trauma Acute Care Surg. 2017; in press. ID - ref11 ER - TY - JOUR AU - Gardner, A. n. n. a. K. AU - Ghita, G. a. b. r. i. e. l. a. L. AU - Wang, Z. h. o. n. g. k. a. i. AU - Ozrazgat-Baslanti, T. e. z. c. a. n. AU - Raymond, S. t. e. v. e. n. L. AU - Mankowski, R. o. b. e. r. t. T. AU - Brumback, B. a. b. e. t. t. e. A. AU - Efron, P. h. i. l. i. p. A. AU - Bihorac, A. z. r. a. AU - Moore, F. r. e. d. e. r. i. c. k. A. AU - Anton, S. t. e. p. h. e. n. D. AU - Brakenridge, S. c. o. t. t. C. PY - 2019 DA - 2019// TI - The Development of Chronic Critical Illness Determines Physical Function, Quality of Life, and Long-Term Survival Among Early Survivors of Sepsis in Surgical ICUs* JO - Critical Care Medicine VL - 47 UR - https://doi.org/10.1097/CCM.0000000000003655 DO - 10.1097/CCM.0000000000003655 ID - Gardner2019 ER - TY - JOUR AU - Hawkins, R. B. AU - Raymond, S. L. AU - Stortz, J. A. AU - Horiguchi, H. AU - Brakenridge, S. C. AU - Gardner, A. PY - 2018 DA - 2018// TI - Chronic critical illness and the persistent inflammation, immunosuppression, and catabolism syndrome JO - Front Immunol VL - 9 UR - https://doi.org/10.3389/fimmu.2018.01511 DO - 10.3389/fimmu.2018.01511 ID - Hawkins2018 ER - TY - JOUR AU - Artenstein, A. W. AU - Higgins, T. L. AU - Opal, S. M. PY - 2013 DA - 2013// TI - Sepsis and scientific revolutions JO - Crit Care Med VL - 41 UR - https://doi.org/10.1097/CCM.0b013e31829eb98f DO - 10.1097/CCM.0b013e31829eb98f ID - Artenstein2013 ER - TY - JOUR AU - Hotchkiss, R. S. AU - Colston, E. AU - Yende, S. AU - Angus, D. C. AU - Moldawer, L. L. AU - Crouser, E. D. PY - 2019 DA - 2019// TI - Immune checkpoint inhibition in sepsis: a phase 1b randomized, placebo-controlled, single ascending dose study of antiprogrammed cell death-ligand 1 antibody (BMS-936559) JO - Crit Care Med VL - 47 UR - https://doi.org/10.1097/CCM.0000000000003685 DO - 10.1097/CCM.0000000000003685 ID - Hotchkiss2019 ER - TY - STD TI - Francois B, Jeannet R, Daix T, Walton AH, Shotwell MS, Unsinger J, et al. Interleukin-7 restores lymphocytes in septic shock: the IRIS-7 randomized clinical trial. JCI Insight. 2018;3(5):e98960. ID - ref16 ER - TY - JOUR AU - Efron, P. h. i. l. i. p. A. AU - Mohr, A. l. i. c. i. a. M. AU - Moore, F. r. e. d. e. r. i. c. k. A. AU - Moldawer, L. y. l. e. L. PY - 2015 DA - 2015// TI - The future of murine sepsis and trauma research models JO - Journal of Leukocyte Biology VL - 98 UR - https://doi.org/10.1189/jlb.5MR0315-127R DO - 10.1189/jlb.5MR0315-127R ID - Efron2015 ER - TY - JOUR AU - Stortz, J. A. AU - Raymond, S. L. AU - Mira, J. C. AU - Moldawer, L. L. AU - Mohr, A. M. AU - Efron, P. A. PY - 2017 DA - 2017// TI - Murine models of sepsis and trauma: can we bridge the gap? JO - ILAR J VL - 58 UR - https://doi.org/10.1093/ilar/ilx007 DO - 10.1093/ilar/ilx007 ID - Stortz2017 ER - TY - JOUR AU - Horiguchi, H. AU - Loftus, T. J. AU - Hawkins, R. B. AU - Raymond, S. L. AU - Stortz, J. A. AU - Hollen, M. K. PY - 2018 DA - 2018// TI - Innate immunity in the persistent inflammation, immunosuppression, and catabolism syndrome and its implications for therapy JO - Front Immunol VL - 9 UR - https://doi.org/10.3389/fimmu.2018.00595 DO - 10.3389/fimmu.2018.00595 ID - Horiguchi2018 ER - TY - JOUR AU - Mathias, B. AU - Delmas, A. L. AU - Ozrazgat-Baslanti, T. AU - Vanzant, E. L. AU - Szpila, B. E. AU - Mohr, A. M. PY - 2017 DA - 2017// TI - Human myeloid-derived suppressor cells are associated with chronic immune suppression after severe sepsis/septic shock JO - Ann Surg VL - 265 UR - https://doi.org/10.1097/SLA.0000000000001783 DO - 10.1097/SLA.0000000000001783 ID - Mathias2017 ER - TY - JOUR AU - Salminen, A. AU - Kaarniranta, K. AU - Kauppinen, A. PY - 2018 DA - 2018// TI - The role of myeloid-derived suppressor cells (MDSC) in the inflammaging process JO - Ageing Res Rev VL - 48 UR - https://doi.org/10.1016/j.arr.2018.09.001 DO - 10.1016/j.arr.2018.09.001 ID - Salminen2018 ER - TY - JOUR AU - Cuenca, A. G. AU - Cuenca, A. L. AU - Winfield, R. D. AU - Joiner, D. N. AU - Gentile, L. AU - Delano, M. J. PY - 2014 DA - 2014// TI - Novel role for tumor-induced expansion of myeloid-derived cells in cancer cachexia JO - J Immunol VL - 192 UR - https://doi.org/10.4049/jimmunol.1302895 DO - 10.4049/jimmunol.1302895 ID - Cuenca2014 ER - TY - JOUR AU - Cuenca, A. G. AU - Delano, M. J. AU - Kelly-Scumpia, K. M. AU - Moreno, C. AU - Scumpia, P. O. AU - Laface, D. M. PY - 2011 DA - 2011// TI - A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma JO - Mol Med VL - 17 UR - https://doi.org/10.2119/molmed.2010.00178 DO - 10.2119/molmed.2010.00178 ID - Cuenca2011 ER - TY - JOUR AU - Cuenca, A. G. AU - Moldawer, L. L. PY - 2012 DA - 2012// TI - Myeloid-derived suppressor cells in sepsis: friend or foe? JO - Intensive Care Med VL - 38 UR - https://doi.org/10.1007/s00134-012-2575-3 DO - 10.1007/s00134-012-2575-3 ID - Cuenca2012 ER - TY - JOUR AU - Hotchkiss, R. S. AU - Monneret, G. AU - Payen, D. PY - 2013 DA - 2013// TI - Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy JO - Nat Rev Immunol VL - 13 UR - https://doi.org/10.1038/nri3552 DO - 10.1038/nri3552 ID - Hotchkiss2013 ER - TY - JOUR AU - Jia, B. AU - Zhao, C. AU - Li, G. AU - Kong, Y. AU - Ma, Y. AU - Wang, Q. PY - 2017 DA - 2017// TI - A novel CD48-based analysis of sepsis-induced mouse myeloid-derived suppressor cell compartments JO - Mediat Inflamm VL - 2017 ID - Jia2017 ER - TY - JOUR AU - Peranzoni, E. AU - Zilio, S. AU - Marigo, I. AU - Dolcetti, L. AU - Zanovello, P. AU - Mandruzzato, S. PY - 2010 DA - 2010// TI - Myeloid-derived suppressor cell heterogeneity and subset definition JO - Curr Opin Immunol VL - 22 UR - https://doi.org/10.1016/j.coi.2010.01.021 DO - 10.1016/j.coi.2010.01.021 ID - Peranzoni2010 ER - TY - JOUR AU - Delano, M. J. AU - Scumpia, P. O. AU - Weinstein, J. S. AU - Coco, D. AU - Nagaraj, S. AU - Kelly-Scumpia, K. M. PY - 2007 DA - 2007// TI - MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis JO - J Exp Med VL - 204 UR - https://doi.org/10.1084/jem.20062602 DO - 10.1084/jem.20062602 ID - Delano2007 ER - TY - JOUR AU - Janols, H. AU - Bergenfelz, C. AU - Allaoui, R. AU - Larsson, A. M. AU - Ryden, L. AU - Bjornsson, S. PY - 2014 DA - 2014// TI - A high frequency of MDSCs in sepsis patients, with the granulocytic subtype dominating in gram-positive cases JO - J Leukoc Biol VL - 96 UR - https://doi.org/10.1189/jlb.5HI0214-074R DO - 10.1189/jlb.5HI0214-074R ID - Janols2014 ER - TY - JOUR AU - Patel, J. J. AU - Rosenthal, M. D. AU - McClave, S. A. AU - Martindale, R. G. PY - 2018 DA - 2018// TI - Tempering the clinical effects of early myeloid-derived suppressor cell expansion in severe sepsis and septic shock JO - Am J Respir Crit Care Med VL - 197 UR - https://doi.org/10.1164/rccm.201708-1701LE DO - 10.1164/rccm.201708-1701LE ID - Patel2018 ER - TY - JOUR AU - Stoll, H. AU - Ost, M. AU - Singh, A. AU - Mehling, R. AU - Neri, D. AU - Schafer, I. PY - 2018 DA - 2018// TI - Staphylococcal enterotoxins dose-dependently modulate the generation of myeloid-derived suppressor cells JO - Front Cell Infect Microbiol VL - 8 UR - https://doi.org/10.3389/fcimb.2018.00321 DO - 10.3389/fcimb.2018.00321 ID - Stoll2018 ER - TY - JOUR AU - Schrijver, I. T. AU - Theroude, C. AU - Roger, T. PY - 2019 DA - 2019// TI - Myeloid-derived suppressor cells in sepsis JO - Front Immunol VL - 10 UR - https://doi.org/10.3389/fimmu.2019.00327 DO - 10.3389/fimmu.2019.00327 ID - Schrijver2019 ER - TY - JOUR AU - Zhang, C. AU - Wang, S. AU - Liu, Y. AU - Yang, C. PY - 2016 DA - 2016// TI - Epigenetics in myeloid derived suppressor cells: a sheathed sword towards cancer JO - Oncotarget. VL - 7 ID - Zhang2016 ER - TY - JOUR AU - Gazzar, M. PY - 2014 DA - 2014// TI - microRNAs as potential regulators of myeloid-derived suppressor cell expansion JO - Innate Immun VL - 20 UR - https://doi.org/10.1177/1753425913489850 DO - 10.1177/1753425913489850 ID - Gazzar2014 ER - TY - JOUR AU - Brudecki, L. AU - Ferguson, D. A. AU - McCall, C. E. AU - Gazzar, M. PY - 2012 DA - 2012// TI - Myeloid-derived suppressor cells evolve during sepsis and can enhance or attenuate the systemic inflammatory response JO - Infect Immun VL - 80 UR - https://doi.org/10.1128/IAI.00239-12 DO - 10.1128/IAI.00239-12 ID - Brudecki2012 ER - TY - JOUR AU - Stortz, J. A. AU - Murphy, T. J. AU - Raymond, S. L. AU - Mira, J. C. AU - Ungaro, R. AU - Dirain, M. L. PY - 2018 DA - 2018// TI - Evidence for persistent immune suppression in patients who develop chronic critical illness after sepsis JO - Shock. VL - 49 UR - https://doi.org/10.1097/SHK.0000000000000981 DO - 10.1097/SHK.0000000000000981 ID - Stortz2018 ER - TY - JOUR AU - Croft, C. A. AU - Moore, F. A. AU - Efron, P. A. AU - Marker, P. S. AU - Gabrielli, A. AU - Westhoff, L. S. PY - 2014 DA - 2014// TI - Computer versus paper system for recognition and management of sepsis in surgical intensive care JO - J Trauma Acute Care Surg VL - 76 UR - https://doi.org/10.1097/TA.0000000000000121 DO - 10.1097/TA.0000000000000121 ID - Croft2014 ER - TY - JOUR AU - Fitousis, K. AU - Moore, L. J. AU - Hall, J. AU - Moore, F. A. AU - Pass, S. PY - 2010 DA - 2010// TI - Evaluation of empiric antibiotic use in surgical sepsis JO - Am J Surg VL - 200 UR - https://doi.org/10.1016/j.amjsurg.2010.09.001 DO - 10.1016/j.amjsurg.2010.09.001 ID - Fitousis2010 ER - TY - JOUR AU - Levy, M. M. AU - Fink, M. P. AU - Marshall, J. C. AU - Abraham, E. AU - Angus, D. AU - Cook, D. PY - 2003 DA - 2003// TI - 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference JO - Crit Care Med VL - 31 UR - https://doi.org/10.1097/01.CCM.0000050454.01978.3B DO - 10.1097/01.CCM.0000050454.01978.3B ID - Levy2003 ER - TY - JOUR AU - Ferreira, F. L. AU - Bota, D. P. AU - Bross, A. AU - Melot, C. AU - Vincent, J. L. PY - 2001 DA - 2001// TI - Serial evaluation of the SOFA score to predict outcome in critically ill patients JO - JAMA. VL - 286 UR - https://doi.org/10.1001/jama.286.14.1754 DO - 10.1001/jama.286.14.1754 ID - Ferreira2001 ER - TY - JOUR AU - Batchu, R. B. AU - Gruzdyn, O. V. AU - Mahmud, E. M. AU - Chukr, F. AU - Dachepalli, R. AU - Manmari, S. K. PY - 2018 DA - 2018// TI - Inhibition of Interleukin-10 in the tumor microenvironment can restore mesothelin chimeric antigen receptor T cell activity in pancreatic cancer in vitro JO - Surgery. VL - 163 UR - https://doi.org/10.1016/j.surg.2017.10.056 DO - 10.1016/j.surg.2017.10.056 ID - Batchu2018 ER - TY - JOUR AU - Brinke, A. AU - Marek-Trzonkowska, N. AU - Mansilla, M. J. AU - Turksma, A. W. AU - Piekarska, K. AU - Iwaszkiewicz-Grzes, D. PY - 2017 DA - 2017// TI - Monitoring T-cell responses in translational studies: optimization of dye-based proliferation assay for evaluation of antigen-specific responses JO - Front Immunol VL - 8 UR - https://doi.org/10.3389/fimmu.2017.01870 DO - 10.3389/fimmu.2017.01870 ID - Brinke2017 ER - TY - STD TI - Agarwal V, Bell GW, Nam JW, Bartel DP. Predicting effective microRNA target sites in mammalian mRNAs. Elife. 2015;4:e05005. ID - ref43 ER - TY - JOUR AU - Uhel, F. AU - Azzaoui, I. AU - Gregoire, M. AU - Pangault, C. AU - Dulong, J. AU - Tadie, J. M. PY - 2017 DA - 2017// TI - Early expansion of circulating granulocytic myeloid-derived suppressor cells predicts development of nosocomial infections in patients with sepsis JO - Am J Respir Crit Care Med VL - 196 UR - https://doi.org/10.1164/rccm.201606-1143OC DO - 10.1164/rccm.201606-1143OC ID - Uhel2017 ER - TY - JOUR AU - Gabrilovich, D. I. PY - 2017 DA - 2017// TI - Myeloid-derived suppressor cells JO - Cancer Immunol Res VL - 5 UR - https://doi.org/10.1158/2326-6066.CIR-16-0297 DO - 10.1158/2326-6066.CIR-16-0297 ID - Gabrilovich2017 ER - TY - JOUR AU - Yamauchi, Y. AU - Safi, S. AU - Blattner, C. AU - Rathinasamy, A. AU - Umansky, L. AU - Juenger, S. PY - 2018 DA - 2018// TI - Circulating and tumor myeloid-derived suppressor cells in resectable non-small cell lung Cancer JO - Am J Respir Crit Care Med VL - 198 UR - https://doi.org/10.1164/rccm.201708-1707OC DO - 10.1164/rccm.201708-1707OC ID - Yamauchi2018 ER - TY - JOUR AU - Veglia, F. AU - Perego, M. AU - Gabrilovich, D. PY - 2018 DA - 2018// TI - Myeloid-derived suppressor cells coming of age JO - Nat Immunol VL - 19 UR - https://doi.org/10.1038/s41590-017-0022-x DO - 10.1038/s41590-017-0022-x ID - Veglia2018 ER - TY - JOUR AU - Dumitru, C. A. AU - Moses, K. AU - Trellakis, S. AU - Lang, S. AU - Brandau, S. PY - 2012 DA - 2012// TI - Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology JO - Cancer Immunol Immunother VL - 61 UR - https://doi.org/10.1007/s00262-012-1294-5 DO - 10.1007/s00262-012-1294-5 ID - Dumitru2012 ER - TY - JOUR AU - Talmadge, J. E. AU - Gabrilovich, D. I. PY - 2013 DA - 2013// TI - History of myeloid-derived suppressor cells JO - Nat Rev Cancer VL - 13 UR - https://doi.org/10.1038/nrc3581 DO - 10.1038/nrc3581 ID - Talmadge2013 ER - TY - JOUR AU - Park, M. J. AU - Lee, S. H. AU - Kim, E. K. AU - Lee, E. J. AU - Baek, J. A. AU - Park, S. H. PY - 2018 DA - 2018// TI - Interleukin-10 produced by myeloid-derived suppressor cells is critical for the induction of Tregs and attenuation of rheumatoid inflammation in mice JO - Sci Rep VL - 8 UR - https://doi.org/10.1038/s41598-018-21856-2 DO - 10.1038/s41598-018-21856-2 ID - Park2018 ER - TY - JOUR AU - Angus, D. C. AU - Wax, R. S. PY - 2001 DA - 2001// TI - Epidemiology of sepsis: an update JO - Crit Care Med VL - 29 UR - https://doi.org/10.1097/00003246-200107001-00035 DO - 10.1097/00003246-200107001-00035 ID - Angus2001 ER - TY - JOUR AU - Umansky, V. i. k. t. o. r. AU - Blattner, C. a. r. o. l. i. n. AU - Gebhardt, C. h. r. i. s. t. o. f. f. e. r. AU - Utikal, J. o. c. h. e. n. PY - 2016 DA - 2016// TI - The Role of Myeloid-Derived Suppressor Cells (MDSC) in Cancer Progression JO - Vaccines VL - 4 UR - https://doi.org/10.3390/vaccines4040036 DO - 10.3390/vaccines4040036 ID - Umansky2016 ER - TY - JOUR AU - Kim, Y. S. AU - Kim, Y. J. AU - Lee, J. M. AU - Kim, E. K. AU - Park, Y. J. AU - Choe, S. K. PY - 2012 DA - 2012// TI - Functional changes in myeloid-derived suppressor cells (MDSCs) during tumor growth: FKBP51 contributes to the regulation of the immunosuppressive function of MDSCs JO - J Immunol VL - 188 UR - https://doi.org/10.4049/jimmunol.1103040 DO - 10.4049/jimmunol.1103040 ID - Kim2012 ER - TY - STD TI - Cross D, Drury R, Hill J, Pollard AJ. Epigenetics in Sepsis: Understanding Its Role in Endothelial Dysfunction, Immunosuppression, and Potential Therapeutics. Front Immunol. 2019;10:1363. ID - ref54 ER - TY - JOUR AU - Bronte, V. AU - Brandau, S. AU - Chen, S. H. AU - Colombo, M. P. AU - Frey, A. B. AU - Greten, T. F. PY - 2016 DA - 2016// TI - Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards JO - Nat Commun VL - 7 UR - https://doi.org/10.1038/ncomms12150 DO - 10.1038/ncomms12150 ID - Bronte2016 ER - TY - JOUR AU - Maples, K. R. AU - Mason, R. P. PY - 1988 DA - 1988// TI - Free radical metabolite of uric acid JO - J Biol Chem VL - 263 ID - Maples1988 ER - TY - JOUR AU - Hübner, M. a. x. AU - Tomasi, R. o. l. a. n. d. AU - Effinger, D. a. v. i. d. AU - Wu, T. i. n. g. t. i. n. g. AU - Klein, G. r. e. g. o. r. AU - Bender, M. a. r. t. i. n. AU - Kilger, E. r. i. c. h. AU - Juchem, G. e. r. d. AU - Schwedhelm, E. d. z. a. r. d. AU - Kreth, S. i. m. o. n. e. PY - 2019 DA - 2019// TI - Myeloid-Derived Suppressor Cells Mediate Immunosuppression After Cardiopulmonary Bypass JO - Critical Care Medicine VL - 47 UR - https://doi.org/10.1097/CCM.0000000000003820 DO - 10.1097/CCM.0000000000003820 ID - Hübner2019 ER - TY - JOUR AU - Serafini, P. AU - Meckel, K. AU - Kelso, M. AU - Noonan, K. AU - Califano, J. AU - Koch, W. PY - 2006 DA - 2006// TI - Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function JO - J Exp Med VL - 203 UR - https://doi.org/10.1084/jem.20061104 DO - 10.1084/jem.20061104 ID - Serafini2006 ER - TY - JOUR AU - Meyer, C. AU - Sevko, A. AU - Ramacher, M. AU - Bazhin, A. V. AU - Falk, C. S. AU - Osen, W. PY - 2011 DA - 2011// TI - Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model JO - Proc Natl Acad Sci U S A VL - 108 UR - https://doi.org/10.1073/pnas.1108121108 DO - 10.1073/pnas.1108121108 ID - Meyer2011 ER - TY - JOUR AU - Lin, S. AU - Wang, J. AU - Wang, L. AU - Wen, J. AU - Guo, Y. AU - Qiao, W. PY - 2017 DA - 2017// TI - Phosphodiesterase-5 inhibition suppresses colonic inflammation-induced tumorigenesis via blocking the recruitment of MDSC JO - Am J Cancer Res VL - 7 ID - Lin2017 ER - TY - JOUR AU - Chen, H. -. M. AU - Ma, G. AU - Gildener-Leapman, N. AU - Eisenstein, S. AU - Coakley, B. A. AU - Ozao, J. PY - 2015 DA - 2015// TI - Myeloid-derived suppressor cells as an immune parameter in patients with concurrent sunitinib and stereotactic body radiotherapy JO - Clin Cancer Res VL - 21 UR - https://doi.org/10.1158/1078-0432.CCR-14-2742 DO - 10.1158/1078-0432.CCR-14-2742 ID - Chen2015 ER - TY - JOUR AU - Sheedy, F. J. AU - Palsson-McDermott, E. AU - Hennessy, E. J. AU - Martin, C. AU - O’Leary, J. J. AU - Ruan, Q. PY - 2010 DA - 2010// TI - Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21 JO - Nat Immunol VL - 11 UR - https://doi.org/10.1038/ni.1828 DO - 10.1038/ni.1828 ID - Sheedy2010 ER - TY - JOUR AU - Medina, P. P. AU - Nolde, M. AU - Slack, F. J. PY - 2010 DA - 2010// TI - OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma JO - Nature. VL - 467 UR - https://doi.org/10.1038/nature09284 DO - 10.1038/nature09284 ID - Medina2010 ER - TY - JOUR AU - Han, Y. C. AU - Park, C. Y. AU - Bhagat, G. AU - Zhang, J. AU - Wang, Y. AU - Fan, J. B. PY - 2010 DA - 2010// TI - microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia JO - J Exp Med VL - 207 UR - https://doi.org/10.1084/jem.20090831 DO - 10.1084/jem.20090831 ID - Han2010 ER - TY - JOUR AU - Velu, C. S. AU - Baktula, A. M. AU - Grimes, H. L. PY - 2009 DA - 2009// TI - Gfi1 regulates miR-21 and miR-196b to control myelopoiesis JO - Blood. VL - 113 UR - https://doi.org/10.1182/blood-2008-11-190215 DO - 10.1182/blood-2008-11-190215 ID - Velu2009 ER - TY - JOUR AU - McClure, C. AU - Brudecki, L. AU - Ferguson, D. A. AU - Yao, Z. Q. AU - Moorman, J. P. AU - McCall, C. E. PY - 2014 DA - 2014// TI - MicroRNA 21 (miR-21) and miR-181b couple with NFI-A to generate myeloid-derived suppressor cells and promote immunosuppression in late sepsis JO - Infect Immun VL - 82 UR - https://doi.org/10.1128/IAI.01495-14 DO - 10.1128/IAI.01495-14 ID - McClure2014 ER - TY - JOUR AU - Weng, H. AU - Lal, K. AU - Yang, F. F. AU - Chen, J. PY - 2015 DA - 2015// TI - The pathological role and prognostic impact of miR-181 in acute myeloid leukemia JO - Cancer Genet VL - 208 UR - https://doi.org/10.1016/j.cancergen.2014.12.006 DO - 10.1016/j.cancergen.2014.12.006 ID - Weng2015 ER - TY - JOUR AU - Loftus, T. J. AU - Mira, J. C. AU - Ozrazgat-Baslanti, T. AU - Ghita, G. L. AU - Wang, Z. AU - Stortz, J. A. PY - 2017 DA - 2017// TI - Sepsis and Critical Illness Research Center investigators: protocols and standard operating procedures for a prospective cohort study of sepsis in critically ill surgical patients JO - BMJ Open VL - 7 UR - https://doi.org/10.1136/bmjopen-2016-015136 DO - 10.1136/bmjopen-2016-015136 ID - Loftus2017 ER -