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Table 2 Primary outcome parameters (vasoplegia)

From: In-line filtration of intravenous infusion may reduce organ dysfunction of adult critical patients

 

Fine filter cohort (n = 1506)

Control filter cohort (n = 1506)

P valuea

P valueb

Vasoplegia (n; %)

316; 21.0% (19.0–23.1%)

295; 19.6% (17.6–21.7%)

> 0.20, RR 1.07 (0.93–1.23)

> 0.20, OR 1.05 (0.87–1.27)

Maximum rate of norepinephrine (μg/kg/min)

0.09 (0.03–0.23), 0.16 ± 0.01

0.05 (0.00–0.20), 0.14 ± 0.01

< 0.01, MW 0.58 (0.56–0.60)

< 0.01

Patients receiving norepinephrine (n; %)

1249; 82.9% (80.9–84.8%)

1000; 66.4% (64.0–68.8%)

< 0.01, RR 1.25 (1.20–1.30)

< 0.01, OR 1.17 (1.14–1.21)

Patients receiving methylene blue (n; %)

147; 9.8% (8.3–11.4%)

153; 10.2% (8.7–11.8%)

> 0.20

> 0.20

  1. This table shows the occurrence rate of the primary endpoint vasoplegia and the total amount of chosen vasopressor drugs between the fine filter and control filter group. Rate of vasoplegia was not significantly different between the fine filter and the control filter cohort
  2. Data are presented as the mean ± standard error, as the median (first quartile–third quartile), as the percentage rates (with 95% confidence intervals), or as the number (n) of patients, where indicated
  3. aP values were calculated using the Wilcoxon-Mann-Whitney U test for equality of means, Pearson’s chi-square test, or Fisher’s exact test, as appropriate. Risk ratios or Mann-Whitney effect estimators (Delong method for AUC) are provided as appropriate
  4. bP values were calculated using the Wald test. The regression model includes cohort, age, sex, and surgery as regression variables. Odds ratios are provided if appropriate and if the P value is significant
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Critical Care

ISSN: 1364-8535