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Table 1 Baseline characteristics of patients (propensity score matched)

From: In-line filtration of intravenous infusion may reduce organ dysfunction of adult critical patients

 

Fine filter cohort (n = 1506)

Control filter cohort (n = 1506)

P valuea

Age (years)

68 (58.0–75), 65.7 ± 0.3

66 (57–74), 63.9 ± 0.3

Approximate match, P <  0.01, MW 0.54 (0.52–0.56)

Male sex (n; %)

1081; 71.8%

1081; 71.8%

Exact match, P = 1.00

Surgery groups (n; %)

  

Exact match, P = 1.00

 No surgery

204; 13.5%

204; 13.5%

 

 Dermatology, ophthalmology

4; 0.3%

4; 0.3%

 

 Neurosurgery

1; 0.1%

1; 0.1%

 

 Otorhinolaryngology

16; 1.1%

16; 1.1%

 

 Thoracic

14; 0.9%

14; 0.9%

 

 Cardiac

617; 41.0%

617; 41.0%

 

 Vascular

48; 3.2%

48; 3.2%

 

 Visceral and endocrine

46; 3.1%

46; 3.1%

 

 Urology

12; 0.8%

12; 0.8%

 

 Gynaecology

1; 0.1%

1; 0.1%

 

 Obstetric

3; 0.2%

3; 0.2%

 

 Oral and maxillofacial

2; 0.1%

2; 0.1%

 

 Trauma/orthopaedic

32; 2.1%

32; 2.1%

 

 Other surgery

1; 0.1%

1; 0.1%

 

 Mixed

505; 33.5%

505; 33.5%

 

 Discarded for matching (n)

115

88

 

Initial SOFA scoreb

8 (6–11)

8 (5–11)

> 0.20

Initial SAPS IIc

46 (33.5–58)

41 (30–56)

< 0.01, MW 0.56 (0.52–0.59)

Initial TISS-10d

18 (14–26)

21 (14–26)

> 0.20

Initial TISS-28e

39 (33–45)

38 (32.5–45)

0.17

Initial Horowitz indexf

317 (234–393)

314 (232–383)

> 0.20

Initial creatinine value (mg/dl)g

0.90 (0.72–1.17)

0.90 (0.72–1.20)

> 0.20

Initial delirium scoreh

2 (0–5)

1 (0–3)

< 0.01, MW 0.55 (0.51–0.59)

Initial interleukin-6 value (ng/l)i

284.2 (135.9–605.2)

284.2 (131.2–672.0)

> 0.20

  1. This table shows the distribution of subjects between the fine filter and control filter cohort by demographic characteristics, surgery category, and baselines for multi-organ scores and for chosen laboratory values at admission. Age, delirium score, and SAPS II at admission were significantly worse for the fine filter cohort
  2. Data are presented as the mean ± standard error, as the median (first quartile–third quartile), as the percentage rates (with 95% confidence intervals), or as the number (n) of patients, where indicated
  3. aP values were calculated using the Wilcoxon-Mann-Whitney U test for equality of means, Pearson’s chi-square test, or Fisher’s exact test, as appropriate. Odds ratios or Mann-Whitney effect estimators (Delong method for AUC between 0 and 1) are provided as appropriate and only if the P value is significant
  4. bAvailable patients with SOFA score (%): 30.2 (fine filter) and 39.6 (control filter)
  5. cAvailable patients with SAPS II score (%): 36.6 (fine filter) and 44.4 (control filter)
  6. dAvailable patients with TISS-10 score (%): 32.3 (fine filter) and 43.0 (control filter)
  7. eAvailable patients with TISS-28 score (%): 32.3 (fine filter) and 43.0 (control filter)
  8. fAvailable patients with Horowitz index (%): 86.8 (fine filter) and 72.8 (control filter)
  9. gAvailable patients with creatinine value before dialysis (%): 99.1 (fine filter) and 99.1 (control filter)
  10. hAvailable patients with delirium score (%): 20.5 (fine filter) and 52.5 (control filter)
  11. iAvailable patients with interleukin-6 value (%): 98.4 (fine filter) and 98.2 (control filter)