Table 3 Patient subgroups stratified by NEWS and MR-proADM
Patient subgroups | Patient populations stratified by NEWS and MR-proADM | |||||||
|---|---|---|---|---|---|---|---|---|
MR-proADM (nmol/L) | NEWS (points) | MR-proADM (nmol/L) | NEWS (points) | MR-proADM (nmol/L) | NEWS (points) | MR-proADM (nmol/L) | NEWS (points) | |
< 1.77 | < 5 | ≥ 1.77 | < 5 | < 1.77 | ≥ 5 | ≥ 1.77 | ≥ 5 | |
Population, N (%) | 425 (62.1%) | 74 (10.8%) | 100 (14.6%) | 85 (12.8%) | ||||
Antibiotic administration, N (%) | 266 (62.6%) | 63 (85.1%) | 94 (94.0%) | 82 (96.5%) | ||||
Time to antibiotic administration (min) (median [Q1–Q4]) | 180 [90 – 342] | 205.5 [111 – 300] | 210 [142 – 315] | 180 [100 – 300] | ||||
Antibiotic administration < 180 min, N (%) | 108 (40.6%) | 26 (41.3%) | 30 (31.9%) | 33 (40.2%) | ||||
i.v. to oral antibiotic change (days) (median [Q1–Q4]) | 1.5 [1 – 4] | 4.0 [0 – 6.75] | 4 [2 – 6] | 3.5 [0 – 4.5] | ||||
Hospitalisation, N (%) | 260 (61.2%) | 63 (85.1%) | 93 (93.0%) | 82 (96.5%) | ||||
Length of hospitalisation (days) (median [Q1–Q4]) | 1 [0 – 5] | 6 [3 – 11] | 7 [4 – 10] | 7 [4 – 13] | ||||
Infection-related readmission, N (%) | 25 (5.9%) | 14 (18.9%) | 3 (3.0%) | 9 (10.6%) | ||||
ICU admission, N (%) | 7 (1.6%) | 6 (8.1%) | 2 (2.0%) | 8 (9.4%) | ||||
Time to ICU admission (days) (median [Q1–Q4]) | 13 [2 – 20] | 1.5 [1 – 5] | 9.5 [4.75 – 14.25] | 0 [0 – 0] | ||||
Number of immediate ICU admissions, N (%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 7 (30.4%) | ||||
Number of delayed ICU admissions, N (%) | 2 (8.7%) | 5 (21.7%) | 1 (4.3%) | 0 (0.0%) | ||||
Number of late ICU admissions, N (%) | 5 (21.7%) | 1 (4.3%) | 1 (4.3%) | 1 (4.3%) | ||||
Infection-related 28-day mortality, N (%) | 0 (0.0%) | 10 (13.5%) | 6 (6.0%) | 14 (16.5%) | ||||
Hospital mortality, N (%) | 1 (0.2%) | 10 (13.5%) | 9 (9.0%) | 15 (17.6%) | ||||
Disease progression, N (%) | 21 (4.9%) | 22 (29.7%) | 12 (12.0%) | 24 (28.2%) | ||||