Dynamic hyperinflation and intrinsic positive end-expiratory pressure in ARDS patients

Table 3 Computed tomography data in patients with and without intrinsic PEEP

	Patients with intrinsic PEEP (n = 87)	Patients without intrinsic PEEP (n = 130)	P_PEEPi	P_PEEP	P_{PEEPix PEEP}
Total weight (g)			0.72	N.A.	N.A.
5 cmH₂O	1366 [1151–1666]	1411 [1172–1674]
Total gas volume (mL)			0.79	N.A.	N.A.
5 cmH₂O	961 [701–1535]	973 [659–1433]
Non-inflated tissue (%)			0.242	*< 0.001*	0.301
5 cmH₂O	39 [26–53]	43 [33–55]
45 cmH₂O	25 [18–35]	27 [15–38]
Poorly inflated tissue (%)			0.815	*< 0.001*	0.490
5 cmH₂O	30 [23–39]	28 [21–40]
45 cmH₂O	21 [18–33]	25 [19–35]
Well-inflated tissue (%)			0.203	*< 0.001*	0.888
5 cmH₂O	26 [15–40]	25 [14–34]
45 cmH₂O	43 [37–56]	43 [34–55]
Over-inflated tissue (%)			0.814	*< 0.001*	0.149
5 cmH₂O	0.01 [0–0.13]	0.01 [0–0.11]
45 cmH₂O	0.7 [0.21–4.17]	1.49 [0.36–4.60]

Data are expressed as median [I.Q. range] as appropriate
Two-way repeated measures analysis of variance (ANOVA) followed by all pairwise multiple comparison procedures (Holm-Sidak method) was used for analysis
p < 0.05 raising airway pressure from 5 to 45 cmH₂O
There are no significant interactions
n sample size, PEEP positive end-expiratory pressure
Italics: for all the statistical data
Bold italics: for statistical significant data

ISSN: 1364-8535