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Table 1 Baseline characteristics of the study population in relation to the presence of intrinsic PEEP

From: Dynamic hyperinflation and intrinsic positive end-expiratory pressure in ARDS patients

 Total population (n = 217)Patients with intrinsic PEEP (n = 87)Patients without intrinsic PEEP (n = 130)p
Age (yr)61 [48–73]60 [48–61]62 [48–73]0.69
Female % (n)32 (69)28 (24)35 (45)0.30
Height (cm)170 [162–177]170 [163–180]170 [162–175]0.34
BMI (kg/m2)25 [22–29]27 [23–29]24 [22–28]0.004
Intensive care unit stay (days)18 [18–26]19 [10–28]17 [10–25]0.58
SAPS II score40 [32–53]41 [33–50]40 [32–53]0.82
Hospital mortality % (n)46 (99)46 (47)40 (52)0.05
PaO2/FiO2173 [132–224]159 [119–193]188 [142–225]0.008
PaCO2 (mmHg)42 [37–49]44 [39–5141 [36–48]0.005
ARDS category % (n)0.09
 • Mild18 (40)16 (14)15 (20) 
 • Moderate62 (135)58 (50)65 (85) 
 • Severe20 (42)26 (23)20 (25) 
Cause of ARDS % (n)   0.78
 • Pulmonary57 (123)55 (48)58 (75) 
 • Extrapulmonary43 (94)45 (39)42 (55) 
Respiratory rate (breath/min)16 [14–20]18 [16–21]15 [12–20]< 0.0001
Tidal volume (mL)500 [430–586]480 [420–550]500 [450–600]0.03
Tidal volume/body weight (mL/kg)7.8 [6.8–8.8]7.6 [6.7–8.3]7.9 [6.9–9.4]0.0095
Clinical PEEP (cmH2O)10 [10–12]10 [10–12]10 [10–12]0.24
Minute ventilation (L min−1)8.5 [7.2–10.2]9.0 [7.6–11-6]8.2 [6.8–9.7]0.001
Respiratory system compliance (mL cmH2O−1)38 [32–50]37 [30–45]41 [33–51]0.11
  1. Student’s t test or Mann-Whitney rank sum test, as appropriate, were used to analyze continuous variables and the chi-square or Fisher’s exact test, as appropriate, for non-continuous variables. Data are expressed as mean (standard deviation) or median [I.Q. range] as appropriate
  2. N sample size, yr years, BMI body mass index, ARDS acute respiratory distress syndrome, SAPS Simplified Acute Physiology Score
  3. Italics: for all the statistical data
  4. Bold italics: for statistical significant data