From: Candida bloodstream infection under veno-arterial ECMO therapy
All patients (n = 150) | Patients with Candida BSI (n = 4) | |
---|---|---|
Age (years) | 58 [48–69] | 50 [40–57] |
BMI (kg/m2) | 25 [23–29] | 28 [26–29] |
Long-term corticosteroid therapy | 7 (5) | 0 (0) |
SAPS II | 54 [38–70] | 41 [35–49] |
SOFA score at day 0 | 13 [11–15] | 12 [12–12] |
Arterial lactate level at day 0 (mmol/L) | 5 [3–9] | 6 [3–10] |
VA-ECMO for post-cardiotomy shock | 65 (43) | 2 (50) |
VA-ECMO for medical reason | 85 (57) | 2 (50) |
Refractory cardiac arrest | 39 (26) | 1 (25) |
Graft failure after heart transplantation | 14 (9) | 0 (0) |
Intra-aortic balloon pump | 26 (17) | 0 (0) |
KDIGO stage at day 0 | ||
0 | 52 (35) | 2 (50) |
1 | 40 (27) | 0 (0) |
2 | 21 (14) | 1 (25) |
3 | 32 (22) | 1 (25) |
RRT during VA-ECMO course | 63 (42) | 3 (75) |
Red blood cell units at day 1 | 4 [0–8] | 9 [5–12] |
Upper gastrointestinal tract bleeding | 22 (14) | 3 (75) |
Enteral nutrition in the first 5 days | 128 (86) | 4 (100) |
Acute mesenteric ischemia during ECMO course | 14 (9) | 2 (50) |
Antimicrobial therapy during ECMO course | 134 (89) | 4 (100) |
Pneumonia during VA-ECMO support | 76 (51) | 0 (0) |
At least one extra-pulmonary infection during VA-ECMO support | 68 (45) | 3 (75) |
VA-ECMO support duration (days) | 7 [5–13] | 20 [17–21] |
Mechanical ventilation duration (days) | 14 [6–27] | 19 [18–22] |
ICU mortality | 84 (56) | 3 (75) |