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Table 1 Patients characteristics

From: Candida bloodstream infection under veno-arterial ECMO therapy

  All patients
(n = 150)
Patients with Candida BSI
(n = 4)
Age (years) 58 [48–69] 50 [40–57]
BMI (kg/m2) 25 [23–29] 28 [26–29]
Long-term corticosteroid therapy 7 (5) 0 (0)
SAPS II 54 [38–70] 41 [35–49]
SOFA score at day 0 13 [11–15] 12 [12–12]
Arterial lactate level at day 0 (mmol/L) 5 [3–9] 6 [3–10]
VA-ECMO for post-cardiotomy shock 65 (43) 2 (50)
VA-ECMO for medical reason 85 (57) 2 (50)
 Refractory cardiac arrest 39 (26) 1 (25)
 Graft failure after heart transplantation 14 (9) 0 (0)
Intra-aortic balloon pump 26 (17) 0 (0)
KDIGO stage at day 0
 0 52 (35) 2 (50)
 1 40 (27) 0 (0)
 2 21 (14) 1 (25)
 3 32 (22) 1 (25)
RRT during VA-ECMO course 63 (42) 3 (75)
Red blood cell units at day 1 4 [0–8] 9 [5–12]
Upper gastrointestinal tract bleeding 22 (14) 3 (75)
Enteral nutrition in the first 5 days 128 (86) 4 (100)
Acute mesenteric ischemia during ECMO course 14 (9) 2 (50)
Antimicrobial therapy during ECMO course 134 (89) 4 (100)
Pneumonia during VA-ECMO support 76 (51) 0 (0)
At least one extra-pulmonary infection during VA-ECMO support 68 (45) 3 (75)
VA-ECMO support duration (days) 7 [5–13] 20 [17–21]
Mechanical ventilation duration (days) 14 [6–27] 19 [18–22]
ICU mortality 84 (56) 3 (75)
  1. Data are expressed as median [interquartile 25–75] or number (percentage), as appropriate
  2. Abbreviations: BMI body mass index, BSI bloodstream infection, VA-ECMO veno-arterial extra-corporeal membrane oxygenation, SAPS II Simplified Acute Physiology Score II, SOFA Sequential Organ Failure Assessment, KDIGO Kidney Disease: Improving Global Outcomes, RRT renal replacement therapy, ICU intensive care unit