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Table 1 Patients characteristics

From: Candida bloodstream infection under veno-arterial ECMO therapy

 

All patients

(n = 150)

Patients with Candida BSI

(n = 4)

Age (years)

58 [48–69]

50 [40–57]

BMI (kg/m2)

25 [23–29]

28 [26–29]

Long-term corticosteroid therapy

7 (5)

0 (0)

SAPS II

54 [38–70]

41 [35–49]

SOFA score at day 0

13 [11–15]

12 [12–12]

Arterial lactate level at day 0 (mmol/L)

5 [3–9]

6 [3–10]

VA-ECMO for post-cardiotomy shock

65 (43)

2 (50)

VA-ECMO for medical reason

85 (57)

2 (50)

 Refractory cardiac arrest

39 (26)

1 (25)

 Graft failure after heart transplantation

14 (9)

0 (0)

Intra-aortic balloon pump

26 (17)

0 (0)

KDIGO stage at day 0

 0

52 (35)

2 (50)

 1

40 (27)

0 (0)

 2

21 (14)

1 (25)

 3

32 (22)

1 (25)

RRT during VA-ECMO course

63 (42)

3 (75)

Red blood cell units at day 1

4 [0–8]

9 [5–12]

Upper gastrointestinal tract bleeding

22 (14)

3 (75)

Enteral nutrition in the first 5 days

128 (86)

4 (100)

Acute mesenteric ischemia during ECMO course

14 (9)

2 (50)

Antimicrobial therapy during ECMO course

134 (89)

4 (100)

Pneumonia during VA-ECMO support

76 (51)

0 (0)

At least one extra-pulmonary infection during VA-ECMO support

68 (45)

3 (75)

VA-ECMO support duration (days)

7 [5–13]

20 [17–21]

Mechanical ventilation duration (days)

14 [6–27]

19 [18–22]

ICU mortality

84 (56)

3 (75)

  1. Data are expressed as median [interquartile 25–75] or number (percentage), as appropriate
  2. Abbreviations: BMI body mass index, BSI bloodstream infection, VA-ECMO veno-arterial extra-corporeal membrane oxygenation, SAPS II Simplified Acute Physiology Score II, SOFA Sequential Organ Failure Assessment, KDIGO Kidney Disease: Improving Global Outcomes, RRT renal replacement therapy, ICU intensive care unit