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Table 3 Comparisons of physiological parameters between noninvasive ventilation and control groups

From: A multicenter RCT of noninvasive ventilation in pneumonia-induced early mild acute respiratory distress syndrome

Variables

Group

Baseline (n = 102/98)

2 h (n = 102/98)

12 h (n = 102/98)

24 h (n = 99/95)

48 h (n = 98/94)

72 h (n = 96/93)

pa

PaO2/FiO2, mmHg

NIV

232 (35)

246 (72)

244 (79)

247 (73)

260 (81)

273 (79)

.00

Control

231 (28)

217 (59)

223 (76)

230 (76)

241 (76)

250 (85)

.02

pc

.96

.00

.06

.12

.09

.06

.02b

pH

NIV

7.45 (0.05)

7.44 (0.05)

7.44 (0.04)

7.37 (0.76)

7.44 (0.05)

7.44 (0.04)

.82

Control

7.45 (0.05)

7.45 (0.05)

7.44 (0.05)

7.44 (0.05)

7.44 (0.04)

7.44 (0.04)

.56

pc

.24

.42

.99

.34

.33

.65

.31b

PaCO2, mmHg

NIV

34.5 (5.7)

34.9 (5.9)

36.6 (10.2)

35.2 (6.7)

36.0 (6.1)

36.8 (5.4)

.11

Control

33.5 (4.8)

33.9 (5.6)

34.6 (5.4)

36.3 (10.2)

36.6 (6.6)

36.8 (5.5)

.00

pc

.19

.26

.09

.39

.52

.98

.68b

PaO2, mmHg

NIV

107 (22)

99 (26)

96 (29)

96 (23)

99 (27)

100 (26)

.05

Control

110 (19)

92 (27)

91 (27)

90 (27)

94 (27)

93 (24)

.00

pc

.17

.06

.19

.13

.24

.07

.09b

RR, breaths/min

NIV

25.4 (6.2)

24.5 (5.1)

22.8 (4.7)

23.2 (4.8)

22.6 (4.5)

21.9 (4.5)

.00

Control

25.0 (4.9)

24.0 (3.9)

23.4 (4.6)

22.9 (3.5)

22.4 (3.2)

21.5 (3.2)

.00

pc

.57

.43

.35

.59

.68

.48

.57b

  1. Results are means ± SDs. Total number of patients present in each group at each time point without intubation
  2. NIV noninvasive ventilation, PaO2 partial pressure of arterial oxygen, FiO2 fraction of inspired oxygen
  3. ap for overall comparisons of differences in each group over time
  4. bp for overall comparisons of differences between groups over time
  5. cp for comparisons of differences between groups at each time point