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Table 2 Main outcomes

From: A multicenter RCT of noninvasive ventilation in pneumonia-induced early mild acute respiratory distress syndrome

 

NIV group (n = 102)

Control group (n = 98)

p value

Need for intubation, no. (%)

11 (10.8)

9 (9.2)

0.71

Intubation, no. (%)

9 (8.8)

7 (7.1)

0.66

 Duration to intubation, days, mean (SD)

4.7 (6.7)

2.6 (2.9)

0.38

 Reason for intubation

  PaO2/FiO2 at intubation, mmHg, mean (SD)

120.0 (41.9)

147.6 (35.7)

0.13

  RR at intubation, bpm, mean (SD)

43.8 (7.2)

39.4 (3.6)

0.13

   Patients RR > 35 bpm at intubation, no. (%)

10 (90.9)

8 (88.9)

1.00

  Patients’ pH < 7.35 at intubation, no. (%)

4 (36.4)

1 (11.1)

0.32

  Kelly score > 3 at intubation, no. (%)

4 (36.4)

3 (33.3)

1.00

  Accessory respiratory muscle, no. (%)

8 (72.7)

6 (66.7)

1.00

Mortality

    Death in hospital, no. (%)

7 (6.9)

7 (7.1)

0.95

    Death in ICU, no. (%)

7 (6.9)

7 (7.1)

0.72

     Death of intubated patients, no. (%)

7 (63.6)

7 (77.8)

0.64

Days of intensive care, days, mean (SD)

11.4 (7.5)

8.6 (5.3)

0.22

Days of hospital, days, mean (SD)

16.5 (9.4)

17.2 (10.3)

0.65

Cost for hospitalization, RMB, mean (SD)

47,273 (40965)

60,115 (68418)

0.11

Complications

 Hospital-acquired infection, no. (%)

7 (6.9)

4 (4.1)

0.39

  Hospital-acquired pneumonia

4 (3.9)

2 (2.0)

0.68

  Catheter-related infection

2 (2.0)

1 (1.0)

1.00

 Organ failure, no. (%)

8 (7.8)

13 (13.3)

0.21

  Renal failure

3 (2.9)

4 (4.1)

0.72

  Cardiovascular failure

4 (3.9)

8 (8.2)

0.21

  Hepatic failure

4 (3.9)

4 (4.1)

1.00

  Hematologic failure

5 (4.9)

4 (4.1)

1.00

  Central nervous system failure

1 (1.0)

2 (2.0)

0.62

  1. NIV noninvasive ventilation, RR respiratory rate, PaO2 partial pressure of arterial oxygen, FiO2 fraction of inspired oxygen