Table 1 Patient baseline characteristics
NIV group (n = 102) | Control group (n = 98) | p value | |
|---|---|---|---|
Age, years, mean (SD) | 53 (18.2) | 56 (17.5) | 0.21 |
Male, no. (%) | 69 (66.8) | 62 (64.2) | 0.52 |
Smoking, no. (%) | 34 (33.3) | 25 (25.5) | 0.23 |
Body mass index, kg/m2, mean (SD) | 22.4 (3.2) | 22.3 (4.5) | 0.93 |
Type of pneumonia, no. (%) | |||
Community-acquired | 95 (93.1) | 93 (94.9) | 0.60 |
Hospital-acquired | 7 (6.9) | 5 (5.1) | 0.60 |
Positive culture of pathogen, no. (%) | 23 (22.5) | 7 (7.1) | 0.01 |
Bacteria from the respiratory sample | 9 (9.4) | 15 (16.0) | 0.17 |
Blood culture | 2 (2.0) | 4 (4.2) | 0.37 |
Fungus from the respiratory sample | 13 (16.7) | 6 (8.5) | 0.13 |
Underlying comorbidities, no. (%) | |||
Hypertension | 25 (24.5) | 23 (23.5) | 0.86 |
Diabetes mellitus | 7 (6.9) | 18 (18.4) | 0.01 |
Coronary heart disease | 6 (5.9) | 5 (5.1) | 0.81 |
Chronic heart failure | 1 (1.0) | 2 (2.0) | 0.54 |
Chronic renal insufficiency | 4 (3.9) | 8 (8.2) | 0.21 |
Cancer | 4 (3.9) | 2 (2.0) | 0.44 |
Cerebrovascular disease | 2 (2.0) | 7 (7.1) | 0.08 |
Immunosuppression | 9 (8.8) | 10 (10.2) | 0.74 |
White blood cell count, × 109/L, mean (SD) | 10.7 (5.6) | 10.2 (5.9) | 0.56 |
Neutrophil, × 109/L, mean (SD) | 80.7 (14.6) | 82.7 (12.6) | 0.29 |
Arterial blood gas analysis | |||
pH, mean (SD) | 7.445 (0.052) | 7.453 (0.051) | 0.24 |
PaO2/FiO2, mmHg, mean (SD) | 231.5 (35.0) | 231.3 (27.8) | 0.96 |
PaCO2, mmHg, mean (SD) | 34.5 (5.7) | 33.5 (4.8) | 0.19 |
Biochemistry examination | |||
Albumin, g/L, mean (SD) | 31.3 (5.9) | 30.5 (6.6) | 0.37 |
Alanine aminotransferase, U/L, mean (SD) | 53.7 (62.3) | 47.1 (49.7) | 0.41 |
Aspartate aminotransferase U/L, mean (SD) | 61.7 (107.8) | 57.4 (75.1) | 0.74 |
nT-pro BNP, pg/mL, mean (SD) | 1660 (5476) | 1270 (2363) | 0.64 |
C-reactive protein, mg/dL, mean (SD) | 84.3 (84.8) | 99.3 (160.5) | 0.41 |
Procalcitonin, ng/mL, mean (SD) | 46.5 (211.8) | 12.6 (47.0) | 0.12 |
APACHE II score, mean (SD) | 7.0 (4.3) | 8.1 (4.2) | 0.14 |
Admitted to ICU, no. (%) | 73(71.6) | 79 (80.6) | 0.13 |